(Q36160830)

12 August 2017

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title

The art and design of genetic screens: mouse (English)

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12 August 2017

Benjamin T Kile

1

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Doug Hilton

object named as

Douglas J Hilton

series ordinal

2

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publication date

1 July 2005

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12 August 2017

published in

Nature Reviews Genetics

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12 August 2017

volume

6

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12 August 2017

issue

7

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12 August 2017

page(s)

557-567

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https://scigraph.springernature.com/pub.10.1038/nrg1636

12 August 2017

exact match

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cites work

Initial sequencing and comparative analysis of the mouse genome

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Sequence-based analysis of mutagenized mice

21 January 2018

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Mutation rate and predicted phenotypic target sizes in ethylnitrosourea-treated mice

21 January 2018

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A gene-driven approach to the identification of ENU mutants in the mouse

21 January 2018

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A phenotype-based screen for embryonic lethal mutations in the mouse

21 January 2018

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Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis

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A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

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Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse

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Positional cloning and characterization of mouse mei8, a disrupted allelle of the meiotic cohesin Rec8.

21 January 2018

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Functional genetic analysis of mouse chromosome 11

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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CD36 is a sensor of diacylglycerides

21 January 2018

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Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

21 January 2018

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Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

21 January 2018

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An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

21 January 2018

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Implementing large-scale ENU mutagenesis screens in North America

21 January 2018

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The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor

21 January 2018

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Functional annotation of mammalian genomic DNA sequence by chemical mutagenesis: a fine-structure genetic mutation map of a 1- to 2-cM segment of mouse chromosome 7 corresponding to human chromosome 11p14-p15.

21 January 2018

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X-ray-induced mutations in mouse embryonic stem cells

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Chromosomal deletion complexes in mice by radiation of embryonic stem cells

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Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells

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Nested chromosomal deletions induced with retroviral vectors in mice.

21 January 2018

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Rapid generation of nested chromosomal deletions on mouse chromosome 2.

21 January 2018

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Two new mouse chromosome 11 balancers.

21 January 2018

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Modification of an existing chromosomal inversion to engineer a balancer for mouse chromosome 15.

21 January 2018

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21 January 2018

Mouse ENU mutagenesis

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Combining mutagenesis and genomics in the mouse--closing the phenotype gap.

21 January 2018

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Functional identification of the mouse circadian Clock gene by transgenic BAC rescue

21 January 2018

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Positional cloning of the mouse circadian clock gene

21 January 2018

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Finding the genes that direct mammalian development : ENU mutagenesis in the mouse.

21 January 2018

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Analysis of mouse embryonic patterning and morphogenesis by forward genetics

21 January 2018

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Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model

21 January 2018

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Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor

21 January 2018

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

21 January 2018

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Genome-wide ENU mutagenesis to reveal immune regulators

21 January 2018

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The mouse mahogany locus encodes a transmembrane form of human attractin

21 January 2018

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Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon

21 January 2018

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Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia.

21 January 2018

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Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

21 January 2018

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The art and design of genetic screens: filamentous fungi

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The art and design of genetic screens: yeast

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The art and design of genetic screens: caenorhabditis elegans

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The art and design of genetic screens: Drosophila melanogaster

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Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

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Signal transduction and the fate of the R7 photoreceptor in Drosophila

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Signal transduction during the development of the Drosophila R7 photoreceptor

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c-Myb and p300 regulate hematopoietic stem cell proliferation and differentiation

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R/qtl: QTL mapping in experimental crosses

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The mutagenic action of N-ethyl-N-nitrosourea in the mouse

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Defining and assaying RNAi in mammalian cells

21 January 2018

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Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6

21 January 2018

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Gene-trap mutagenesis: past, present and beyond

21 January 2018

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Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 January 2018

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Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

21 January 2018

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A whole lotta jumpin' goin' on: new transposon tools for vertebrate functional genomics.

21 January 2018

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A gene-driven ENU-based approach to generating an allelic series in any gene

21 January 2018

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Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

21 January 2018

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EMPReSS: European mouse phenotyping resource for standardized screens

21 January 2018

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Mutations in dynein link motor neuron degeneration to defects in retrograde transport

21 January 2018

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The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes

21 January 2018

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Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia

21 January 2018

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Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse

31 March 2020

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Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia

31 March 2020

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Mutation rates at a new set of specific loci in the mouse

31 March 2020

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Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells

31 March 2020

1 reference

Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function

31 March 2020

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Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior

31 March 2020

1 reference

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

31 March 2020

1 reference

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

31 March 2020

1 reference

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

31 March 2020

1 reference

X-ray-induced mutations in mice

31 March 2020

1 reference

A strategy for fine-structure functional analysis of a 6- to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis

31 March 2020

1 reference

Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells--analysis of large deletion around hprt locus of ES cell

31 March 2020

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Engineering a mouse balancer chromosome

31 March 2020

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Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p

31 March 2020

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Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus

31 March 2020

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Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

31 March 2020

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

31 March 2020

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

31 March 2020

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The physical basis of heredity

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG1636

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12 August 2017

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