(Q36164751)

12 August 2017

1 reference

title

Causes and consequences of DNA hypomethylation in human cancer (English)

1 reference

12 August 2017

Wolfgang A Schulz

2

0 references

author name string

Michèle J Hoffmann

series ordinal

1

1 reference

12 August 2017

language of work or name

1 reference

1 June 2005

1 reference

Biochemistry and Cell Biology

12 August 2017

published in

1 reference

12 August 2017

volume

83

1 reference

12 August 2017

issue

3

1 reference

12 August 2017

page(s)

296-321

1 reference

Chromodomains are protein-RNA interaction modules

12 August 2017

cites work

1 reference

Cell-Type-Specific Repression of the Maspin Gene Is Disrupted Frequently by Demethylation at the Promoter Region in Gastric Intestinal Metaplasia and Cancer Cells

21 January 2018

1 reference

Erythropoietin and erythropoietin receptor expression in human prostate cancer

21 January 2018

1 reference

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

21 January 2018

1 reference

Hypoxia-inducible factors and hypoxic cell death in tumour physiology

21 January 2018

1 reference

Role of DNA 5-methylcytosine transferase in cell transformation by fos

21 January 2018

1 reference

The DNA methyltransferases of mammals

21 January 2018

1 reference

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

21 January 2018

1 reference

Demethylation of DNA by decitabine in cancer chemotherapy

21 January 2018

1 reference

Epigenomics and epigenetic therapy of cancer

21 January 2018

1 reference

DNA methyltransferases get connected to chromatin

21 January 2018

1 reference

Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway

21 January 2018

1 reference

Bladder Squamous Cell Carcinomas Express Psoriasin and Externalize it to the Urine

21 January 2018

1 reference

Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis.

21 January 2018

1 reference

CTCF, a candidate trans-acting factor for X-inactivation choice

21 January 2018

1 reference

DNA hypomethylation leads to elevated mutation rates

21 January 2018

1 reference

Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis

21 January 2018

1 reference

Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma

21 January 2018

1 reference

Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma

21 January 2018

1 reference

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

21 January 2018

1 reference

Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors

21 January 2018

1 reference

Epigenetic targets in hematopoietic malignancies

21 January 2018

1 reference

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

21 January 2018

1 reference

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

21 January 2018

1 reference

Lsh, a member of the SNF2 family, is required for genome-wide methylation

21 January 2018

1 reference

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

1 reference

Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndrome

21 January 2018

1 reference

Insulator and silencer sequences in the imprinted region of human chromosome 11p15.5.

21 January 2018

1 reference

DNA methylation in cancer: too much, but also too little

21 January 2018

1 reference

Expression of various genes is controlled by DNA methylation during mammalian development

21 January 2018

1 reference

Hypomethylation and hypermethylation of DNA in Wilms tumors.

21 January 2018

1 reference

High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer

21 January 2018

1 reference

The rise and fall of genomic methylation in cancer.

21 January 2018

1 reference

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting

21 January 2018

1 reference

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

21 January 2018

1 reference

Folic acid, polymorphism of methyl-group metabolism genes, and DNA methylation in relation to GI carcinogenesis

21 January 2018

1 reference

Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer

21 January 2018

1 reference

DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms

21 January 2018

1 reference

The Rb/chromatin connection and epigenetic control: opinion.

21 January 2018

1 reference

Methylation and demethylation in the regulation of genes, cells, and responses in the immune system

21 January 2018

1 reference

DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas

21 January 2018

1 reference

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer

21 January 2018

1 reference

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

1 reference

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

21 January 2018

1 reference

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

21 January 2018

1 reference

Role for DNA methylation in the control of cell type specific maspin expression

21 January 2018

1 reference

Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer

21 January 2018

1 reference

Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors

21 January 2018

1 reference

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

Chromatin targeting of de novo DNA methyltransferases by the PWWP domain

21 January 2018

1 reference

Chromatin remodeling, histone modifications, and DNA methylation-how does it all fit together?

21 January 2018

1 reference

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

21 January 2018

1 reference

Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery

21 January 2018

1 reference

Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

21 January 2018

1 reference

Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression

21 January 2018

1 reference

Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation

21 January 2018

1 reference

Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression

21 January 2018

1 reference

Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes

21 January 2018

1 reference

X inactivation-specific methylation of LINE-1 elements by DNMT3B: implications for the Lyon repeat hypothesis

21 January 2018

1 reference

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

21 January 2018

1 reference

Recent advances in X-chromosome inactivation

21 January 2018

1 reference

Role for BRG1 in cell cycle control and tumor suppression

21 January 2018

1 reference

MLL: a histone methyltransferase disrupted in leukemia

21 January 2018

1 reference

The role of metastasis-associated protein 1 in prostate cancer progression

21 January 2018

1 reference

Multiple mechanisms downregulate CDKN1C in human bladder cancer

21 January 2018

1 reference

Demethylation of MAGE promoters during gastric cancer progression

21 January 2018

1 reference

In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b

21 January 2018

1 reference

Lsh, an epigenetic guardian of repetitive elements

21 January 2018

1 reference

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

1 reference

DNA hypomethylation is prevalent even in low-grade breast cancers

21 January 2018

1 reference

DNA demethylation and pericentromeric rearrangements of chromosome 1.

21 January 2018

1 reference

Worms gang up on bacteria

21 January 2018

1 reference

The von Hippel-Lindau tumor suppressor gene and kidney cancer

21 January 2018

1 reference

DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.

21 January 2018

1 reference

A differentially methylated imprinting control region within the Kcnq1 locus harbors a methylation-sensitive chromatin insulator

21 January 2018

1 reference

Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation.

21 January 2018

1 reference

BRG1 controls the activity of the retinoblastoma protein via regulation of p21CIP1/WAF1/SDI.

21 January 2018

1 reference

Multipoint methylation analysis indicates a distinctive epigenetic phenotype among testicular germ cell tumors and testicular malignant lymphomas

21 January 2018

1 reference

Mobile elements: drivers of genome evolution

21 January 2018

1 reference

Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC-dependent and -independent pathways

21 January 2018

1 reference

Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins

21 January 2018

1 reference

HERV-K(HML-2) GAG/ENV antibodies as indicator for therapy effect in patients with germ cell tumors.

21 January 2018

1 reference

The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer

21 January 2018

1 reference

Another Tie that Binds the MTA Family to Breast Cancer

21 January 2018

1 reference

Emerging roles of MTA family members in human cancers

21 January 2018

1 reference

The power and the promise of DNA methylation markers

21 January 2018

1 reference

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

21 January 2018

1 reference

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

21 January 2018

1 reference

Effects of methylation on expression of TMS1/ASC in human breast cancer cells

21 January 2018

1 reference

Genomic imprinting: CTCF protects the boundaries

21 January 2018

1 reference

Chromatin modification and epigenetic reprogramming in mammalian development

21 January 2018

1 reference

DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma

21 January 2018

1 reference

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

21 January 2018

1 reference

The role of RNA interference in heterochromatic silencing

21 January 2018

1 reference

Role of transposable elements in heterochromatin and epigenetic control

21 January 2018

1 reference

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

21 January 2018

1 reference

The pathogenic potential of endogenous retroviruses: facts and fantasies

21 January 2018

1 reference

Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.

21 January 2018

1 reference

A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer

21 January 2018

1 reference

Erythrocytosis caused by an erythropoietin-producing hepatocellular carcinoma.

21 January 2018

1 reference

Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.

21 January 2018

1 reference

L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas

21 January 2018

1 reference

X chromosome inactivation: theme and variations

21 January 2018

1 reference

Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.

21 January 2018

1 reference

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

21 January 2018

1 reference

Overexpression of metastatic tumor antigen 1 in hepatocellular carcinoma: Relationship to vascular invasion and estrogen receptor-alpha

21 January 2018

1 reference

The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide

21 January 2018

1 reference

Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology.

21 January 2018

1 reference

GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer

21 January 2018

1 reference

Demystified. Human endogenous retroviruses

21 January 2018

1 reference

Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation

21 January 2018

1 reference

Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers

21 January 2018

1 reference

Epigenetic variability and the evolution of human cancer.

21 January 2018

1 reference

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

Biology of mammalian L1 retrotransposons

21 January 2018

1 reference

SVA elements are nonautonomous retrotransposons that cause disease in humans

21 January 2018

1 reference

Demethylation of urokinase promoter as a prognostic marker in patients with breast carcinoma.

21 January 2018

1 reference

DNA methyltransferase and demethylase in human prostate cancer

21 January 2018

1 reference

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

1 reference

21 January 2018

1 reference

Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase

21 January 2018

1 reference

Allosteric Activator Domain of Maintenance Human DNA (Cytosine-5) Methyltransferase and Its Role in Methylation Spreading

21 January 2018

1 reference

The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity

21 January 2018

1 reference

Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.

21 January 2018

1 reference

Imprinting in clusters: lessons from Beckwith-Wiedemann syndrome

21 January 2018

1 reference

CpG methylation is maintained in human cancer cells lacking DNMT1.

21 January 2018

1 reference

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

DNA methylation and autoimmune disease

21 January 2018

1 reference

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

21 January 2018

1 reference

DNA methylation, methyltransferases, and cancer

21 January 2018

1 reference

DNA methylation and chromatin - unraveling the tangled web.

21 January 2018

1 reference

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

1 reference

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

21 January 2018

1 reference

Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro.

21 January 2018

1 reference

Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site.

21 January 2018

1 reference

Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

21 January 2018

1 reference

Alu repeated DNAs are differentially methylated in primate germ cells

21 January 2018

1 reference

Expression of the MTA1 mRNA in advanced lung cancer.

21 January 2018

1 reference

Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling

21 January 2018

1 reference

Does SINE evolution preclude Alu function?

21 January 2018

1 reference

Tumor tissue levels of tissue inhibitor of metalloproteinase-1 as a prognostic marker in primary breast cancer

21 January 2018

1 reference

A CpG-rich RNA and an RNA helicase tightly associated with the DNA demethylation complex are present mainly in dividing chick embryo cells.

21 January 2018

1 reference

Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas

21 January 2018

1 reference

Molecular mechanisms for constitutional chromosomal rearrangements in humans

21 January 2018

1 reference

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome

21 January 2018

1 reference

Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors

21 January 2018

1 reference

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

21 January 2018

1 reference

Transcriptional regulation of the human LINE-1 retrotransposon L1.2B.

21 January 2018

1 reference

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

21 January 2018

1 reference

Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue

21 January 2018

1 reference

RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells

21 January 2018

1 reference

DNA methylation and cancer therapy

21 January 2018

1 reference

DNA demethylation and cancer: therapeutic implications.

21 January 2018

1 reference

High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells

21 January 2018

1 reference

Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer

21 January 2018

1 reference

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

21 January 2018

1 reference

A retrospective study of high mobility group protein I(Y) as progression marker for prostate cancer determined by in situ hybridization

21 January 2018

1 reference

Dna methylation in the immune system

21 January 2018

1 reference

CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1.

21 January 2018

1 reference

Expression of the metastasis-associated MTA1 protein and its relationship to deacetylation of the histone H4 in esophageal squamous cell carcinomas

21 January 2018

1 reference

DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients

21 January 2018

1 reference

Gene silencing in mammalian cells and the spread of DNA methylation

21 January 2018

1 reference

MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas

21 January 2018

1 reference

Characterization of DNA demethylation in normal and cancerous cell lines and the regulatory role of cell cycle proteins in human DNA demethylase activity

21 January 2018

1 reference

DNMT1 is a component of a multiprotein DNA replication complex

21 January 2018

1 reference

21 January 2018

1 reference

Biochemical strategy of hepatomas

21 January 2018

1 reference

DNA demethylation in vitro: involvement of RNA.

21 January 2018

1 reference

Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site

21 January 2018

1 reference

DNA hypomethylation and ovarian cancer biology.

21 January 2018

1 reference

Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma

21 January 2018

1 reference

Asymmetric methylation in the hypermethylated CpG promoter region of the human L1 retrotransposon

21 January 2018

1 reference

Biological functions of melanoma-associated antigens

21 January 2018

1 reference

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

21 January 2018

1 reference

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

21 January 2018

1 reference

Lsh, a modulator of CpG methylation, is crucial for normal histone methylation

21 January 2018

1 reference

A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

21 January 2018

1 reference

Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer

21 January 2018

1 reference

Maspin expression in normal lung and non-small-cell lung cancers: cellular property-associated expression under the control of promoter DNA methylation.

21 January 2018

1 reference

Cytosine methylation and the ecology of intragenomic parasites

21 January 2018

1 reference

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

21 January 2018

1 reference

Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription

21 January 2018

1 reference

Cancer/testis-associated genes: identification, expression profile, and putative function

21 January 2018

1 reference

Expression of maspin in prostate cells is regulated by a positive ets element and a negative hormonal responsive element site recognized by androgen receptor

21 January 2018

1 reference

Retinoblastoma tumor suppressor and genome stability

21 January 2018

1 reference

Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/O05-036

1 reference

12 August 2017

1 reference