(Q36166147)

12 August 2017

Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors (English)

1 reference

12 August 2017

Jonathan A Roberts

1

1 reference

12 August 2017

Richard J Evans

series ordinal

2

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12 August 2017

language of work or name

English

0 references

publication date

1 April 2007

1 reference

12 August 2017

Journal of Neuroscience

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12 August 2017

27

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12 August 2017

15

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12 August 2017

4072-4082

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2092412/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor

1 reference

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An intersubunit zinc binding site in rat P2X2 receptors

2 October 2017

1 reference

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Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

2 October 2017

1 reference

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Molecular determinants of the agonist binding domain of a P2X receptor channel.

2 October 2017

1 reference

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Molecular properties of ATP-gated P2X receptor ion channels

2 October 2017

1 reference

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G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation

2 October 2017

1 reference

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Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia

2 October 2017

1 reference

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P2X2 subunits contribute to fast synaptic excitation in myenteric neurons of the mouse small intestine

2 October 2017

1 reference

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

2 October 2017

1 reference

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Structural basis for partial agonist action at ionotropic glutamate receptors

2 October 2017

1 reference

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Identification of residues contributing to the ATP binding site of Kir6.2.

2 October 2017

1 reference

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Molecular physiology of P2X receptors

2 October 2017

1 reference

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Mutational analysis of the conserved cysteines of the rat P2X2 purinoceptor.

2 October 2017

1 reference

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Point mutations confer loss of ATP-induced human P2X(7) receptor function

2 October 2017

1 reference

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Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface

2 October 2017

1 reference

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On the contribution of the first transmembrane domain to whole-cell current through an ATP-gated ionotropic P2X receptor.

2 October 2017

1 reference

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Amino acid residues involved in gating identified in the first membrane-spanning domain of the rat P2X(2) receptor

2 October 2017

1 reference

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Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

2 October 2017

1 reference

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Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

2 October 2017

1 reference

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The PSIPRED protein structure prediction server

2 October 2017

1 reference

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2 October 2017

The Protein Data Bank

1 reference

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Single channel properties of P2X2 purinoceptors

2 October 2017

1 reference

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Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

2 October 2017

1 reference

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Identification of amino acid residues contributing to the pore of a P2X receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

2 October 2017

1 reference

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Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

2 October 2017

1 reference

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Roles of individual N-glycans for ATP potency and expression of the rat P2X1 receptor.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

Contribution of conserved polar glutamine, asparagine and threonine residues and glycosylation to agonist action at human P2X1 receptors for ATP.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

Neurobiology: triggers for channel opening

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

Molecular dissection of purinergic P2X receptor channels.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

ATP binding at human P2X1 receptors. Contribution of aromatic and basic amino acids revealed using mutagenesis and partial agonists

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

P2X(1) receptor-deficient mice establish the native P2X receptor and a P2Y6-like receptor in arteries

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

The role of positively charged amino acids in ATP recognition by human P2X(1) receptors.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

Identification of Amino Acid Residues Contributing to the ATP-binding Site of a Purinergic P2X Receptor

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2092412

Contribution of conserved glycine residues to ATP action at human P2X1 receptors: mutagenesis indicates that the glycine at position 250 is important for channel function

5 December 2018

1 reference

12 December 2020

A C-terminal lysine that controls human P2X4 receptor desensitization

1 reference

12 December 2020

Role of ectodomain lysines in the subunits of the heteromeric P2X2/3 receptor

1 reference

12 December 2020

Participation of the Lys313-Ile333 sequence of the purinergic P2X4 receptor in agonist binding and transduction of signals to the channel gate

1 reference

12 December 2020

A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method

1 reference

12 December 2020

ATP binding site of P2X channel proteins: structural similarities with class II aminoacyl-tRNA synthetases

1 reference

12 December 2020

10.1523/JNEUROSCI.2310-06.2007

Identifiers

DOI

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

17428985

1 reference