(Q36168620)

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Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.

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1 February 2020

Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study (English)

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1 February 2020

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1 February 2020

Damian J. Tyler

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1 February 2020

George K. Radda

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George K Radda

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1 February 2020

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Helen J Atherton

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1 February 2020

Lisa C Heather

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1 February 2020

Marie A Schroeder

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1 February 2020

Julian L Griffin

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1 February 2020

Kieran Clarke

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1 February 2020

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23 May 2011

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1 February 2020

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1 February 2020

123

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1 February 2020

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1 February 2020

2552-2561

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1 February 2020

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4608046/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Insulin action in hyperthyroidism: a focus on muscle and adipose tissue

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1 October 2017

Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)

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1 October 2017

Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice

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1 October 2017

Peripheral neuropathy in rats exposed to dichloroacetate

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1 October 2017

Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy

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1 October 2017

Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

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1 October 2017

Cardiovascular risk with subclinical hyperthyroidism and hypothyroidism: pathophysiology and management

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Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

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1 October 2017

Cellular action of thyroid hormone on the heart

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1 October 2017

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1 October 2017

Nerve conduction changes in patients with mitochondrial diseases treated with dichloroacetate

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1 October 2017

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

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1 October 2017

Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex

1 reference

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1 October 2017

Influence of the Thyroid State on the Intrinsic Contractile Properties and Energy Stores of the Myocardium*

1 reference

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1 October 2017

Dichloroacetate inhibits glycolysis and augments insulin-stimulated glycogen synthesis in rat muscle

1 reference

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1 October 2017

Fuel selection in animals

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1 October 2017

Molecular biology and biochemistry of pyruvate dehydrogenase complexes.

1 reference

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1 October 2017

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a

1 reference

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1 October 2017

Stimulation of phosphorylation and inactivation of pyruvate dehydrogenase by physiological inhibitors of the pyruvate dehydrogenase reaction

1 reference

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1 October 2017

Stimulation of cardiac myosin adenosine triphosphatase in thyrotoxicosis

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1 October 2017

Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.

1 reference

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2 July 2018

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608046

2 July 2018

Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608046

2 July 2018

Hyperthyroidism facilitates cardiac fatty acid oxidation through altered regulation of cardiac carnitine palmitoyltransferase: studies in vivo and with cardiac myocytes

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2 July 2018

Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

1 reference

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2 July 2018

Glucose utilization by skeletal muscles in vivo in experimental hyperthyroidism in the rat.

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2 July 2018

Mechanisms regulating cardiac fuel selection in hyperthyroidism

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2 July 2018

Effect of thyroid hormone on the turnover of rat liver pyruvate carboxylase and pyruvate dehydrogenase

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2 July 2018

Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart

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23 September 2018

A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608046

23 September 2018

Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication).

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23 September 2018

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23 September 2018

Elevated regional lipolysis in hyperthyroidism

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23 September 2018

When the thyroid speaks, the heart listens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608046

23 September 2018

Fuel-sensing mechanisms integrating lipid and carbohydrate utilization

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23 September 2018

Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

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23 September 2018

Tricarboxylic acid cycle intermediate pool size and estimated cycle flux in human muscle during exercise.

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23 September 2018

In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux.

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23 September 2018

A phosphorus-31 nuclear magnetic resonance study of effects of altered thyroid state on cardiac bioenergetics.

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23 September 2018

A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human

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5 December 2018

Different mechanisms underlie the long-term regulation of pyruvate dehydrogenase kinase (PDHK) by tri-iodothyronine in heart and liver

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https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

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Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

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Residues and metabolism of 19-nortestosterone laurate in steers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

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A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Faster protein and ribosome synthesis in thyroxine-induced hypertrophy of rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

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CINE-MR imaging of the normal and infarcted rat heart using an 11.7 T vertical bore MR system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

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Long-term regulation of pyruvate dehydrogenase kinase by high-fat feeding. Experiments in vivo and in cultured cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactive effects of insulin and triiodothyronine on pyruvate dehydrogenase kinase activity in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo NMR investigation of intramuscular glucose metabolism in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of hypertrophy and diabetes on cardiac pyruvate dehydrogenase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21606392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCULATIONAHA.110.011387

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1 February 2020

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1 February 2020

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1 February 2020

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