(Q36171576)

English

Understanding the molecular determinants of substrate and inhibitor specificities in the Carbapenemase KPC-2: exploring the roles of Arg220 and Glu276.

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Understanding the molecular determinants of substrate and inhibitor specificities in the Carbapenemase KPC-2: exploring the roles of Arg220 and Glu276. (English)

1 reference

Europe PubMed Central

12 August 2017

Krisztina M Papp-Wallace

1

object named as

Krisztina M Papp-Wallace

1 reference

Europe PubMed Central

12 August 2017

Robert A Bonomo

5

object named as

Robert A Bonomo

1 reference

Europe PubMed Central

12 August 2017

author name string

Magdalena A Taracila

2

1 reference

Europe PubMed Central

12 August 2017

Kerri M Smith

3

1 reference

Europe PubMed Central

12 August 2017

Yan Xu

4

1 reference

Europe PubMed Central

12 August 2017

language of work or name

0 references

publication date

11 June 2012

1 reference

Europe PubMed Central

12 August 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

12 August 2017

56

1 reference

Europe PubMed Central

12 August 2017

8

1 reference

Europe PubMed Central

12 August 2017

4428-4438

1 reference

Europe PubMed Central

12 August 2017

Crystal Structures of KPC-2 -Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Emerging carbapenemases: a global perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Elucidating the role of Trp105 in the KPC-2 β-lactamase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Three decades of beta-lactamase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

The continuing challenge of ESBLs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Carbapenemases: the versatile beta-lactamases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A β-Lactamases † , ‡

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Extended-spectrum beta-lactamases: a clinical update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

The structure of β-lactamases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

1 October 2017

Analysis of the plasticity of location of the Arg244 positive charge within the active site of the TEM-1 beta-lactamase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

2 July 2018

Interactions between non-classical beta-lactam compounds and the beta-lactamases of Actinomadura R39 and Streptomyces albus G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

2 July 2018

Race against time to develop new antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

23 September 2018

Containing antimicrobial resistance: a renewed effort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

23 September 2018

Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244. Understanding unique properties of inhibitor resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

23 September 2018

Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421566

23 September 2018

Arginine 220 is a critical residue for the catalytic mechanism of the Streptomyces albus G beta-lactamase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22687511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidation of the role of arginine-244 in the turnover processes of class A beta-lactamases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22687511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.05769-11

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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