(Q36176019)

English

Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22669248%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22669248%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Fred A. Pereira

5

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3 February 2020

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Nancy F Butte

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3 February 2020

author name string

Xiaojun Ma

1

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3 February 2020

Yuezhen Lin

2

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3 February 2020

Ligen Lin

3

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3 February 2020

Guijun Qin

4

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3 February 2020

Morey W Haymond

6

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3 February 2020

Yuxiang Sun

8

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3 February 2020

publication date

5 June 2012

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3 February 2020

American Journal of Physiology - Endocrinology and Metabolism

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Europe PubMed Central

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3 February 2020

303

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3 February 2020

3

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Europe PubMed Central

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3 February 2020

E422-31

1 reference

Europe PubMed Central

PMC publication ID

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3 February 2020

The GHS-R blocker D-[Lys3] GHRP-6 serves as CCR5 chemokine receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Macrophage migration inhibitory factor deficiency protects pancreatic islets from palmitic acid-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

A recent update on the role of ghrelin in glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ablations of ghrelin and ghrelin receptor exhibit differential metabolic phenotypes and thermogenic capacity during aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

The ghrelin O-acyltransferase-ghrelin system: a novel regulator of glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin but not obestatin regulates insulin secretion from INS1 beta cell line via UCP2-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

beta-cell function in obese-hyperglycemic mice [ob/ob Mice].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin in the regulation of body weight and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Effect of des-acyl ghrelin on adiposity and glucose metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin and the short- and long-term regulation of appetite and body weight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Hepatic gene regulation by glucose and polyunsaturated fatty acids: a role for ChREBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Absence of ghrelin protects against early-onset obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Mice lacking ghrelin receptors resist the development of diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Leptin and energy expenditure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Deletion of Ghrelin Impairs neither Growth nor Appetite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Antagonism of ghrelin receptor reduces food intake and body weight gain in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

The rat arcuate nucleus integrates peripheral signals provided by leptin, insulin, and a ghrelin mimetic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Identification of a biochemical link between energy intake and energy expenditure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

An integrated view of beta-cell dysfunction in type-II diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Pancreatic polypeptide and other hormones in pancreas of obese (ob/ob) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Vital microscopy of islet blood flow: catecholamine effects in normal and ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Functional abnormalities of islets of Langerhans of obese hyperglycemic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

1 October 2017

Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Antagonism of ghrelin for glycemic control in type 2 diabetes mellitus?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423126

23 September 2018

Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal metabolism of C-peptide in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological analysis of ghrelin and its receptor distribution in the rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obestatin, Acylated and Total Ghrelin Concentrations in the Perinatal Rat Pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obestatin inhibits feeding but does not modulate GH and corticosterone secretion in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ghrelin administration on decreased growth hormone status in obese animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proghrelin-derived peptides influence the secretion of insulin, glucagon, pancreatic polypeptide and somatostatin: a study on isolated islets from mouse and rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPENDO.00576.2011

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22669248%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22669248%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22669248%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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