(Q36179961)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Matej Orešič

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Antonio Vidal-Puig

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Cristina Martínez-García

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Adriana Izquierdo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Yurena Vivas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Ismael Velasco

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Mark Campbell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Keith Burling

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Fernando Cava

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Manuel Ros

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Gema Medina-Gomez

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

5 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

Disease Models & Mechanisms

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

636-648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

7 February 2020

copyright license

start time

18 May 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3424461/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Medical care costs associated with progression of diabetic nephropathy

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Mechanisms and consequences of hypertriglyceridemia and cellular lipid accumulation in chronic kidney disease and metabolic syndrome

1 October 2017

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PPARgamma-dependent regulation of adenylate cyclase 6 amplifies the stimulatory effect of cAMP on renin gene expression

1 October 2017

1 reference

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Role of triglyceride-rich lipoproteins in diabetic nephropathy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Lipotoxicity in renal proximal tubular cells: relationship between endoplasmic reticulum stress and oxidative stress pathways

1 October 2017

1 reference

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Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells.

1 October 2017

1 reference

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Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective

1 October 2017

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Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome

1 October 2017

1 reference

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Activation of the receptor for parathyroid hormone and parathyroid hormone related protein induces apoptosis via the extrinsic and intrinsic signaling pathway.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Nck proteins maintain the adult glomerular filtration barrier

1 October 2017

1 reference

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The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

It's not how fat you are, it's what you do with it that counts

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Adiponectin regulates albuminuria and podocyte function in mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

PPARs and the kidney in metabolic syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper – Excel-based tool using pair-wise correlations

1 October 2017

1 reference

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Podocyte injury promotes progressive nephropathy in zucker diabetic fatty rats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Interaction with podocin facilitates nephrin signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

1 October 2017

1 reference

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Molecular mechanisms of renal hypertrophy: role of p27Kip1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Podocyte loss and progressive glomerular injury in type II diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Insulin signaling to the glomerular podocyte is critical for normal kidney function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Parathyroid hormone-related protein induces hypertrophy in podocytes via TGF-beta(1) and p27(Kip1): implications for diabetic nephropathy

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease

2 July 2018

1 reference

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A histochemical characterization of malignant tumour mucins as a possible aid in the identification of metastatic deposits.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Apoptosis occurs differentially according to glomerular size in diabetic kidney disease

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

PPARgamma in Kidney Physiology and Pathophysiology.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

A controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Pravastatin for secondary prevention of cardiovascular events in persons with mild chronic renal insufficiency

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Monocyte chemoattractant protein 1 mediates glomerular macrophage infiltration in anti-GBM Ab GN.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Stimulation of phosphatidylcholine biosynthesis in diabetic hypertrophic kidneys

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424461

Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis

23 September 2018

1 reference

12 December 2020

Genetic typing of the mouse ob mutation by PCR and restriction enzyme analysis

1 reference

12 December 2020

Intraglomerular lipid deposition in routine biopsies

1 reference

12 December 2020

Diabetes-induced activation of canonical and noncanonical nuclear factor-kappaB pathways in renal cortex

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis

1 reference

12 December 2020

Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes

1 reference

12 December 2020

Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes

1 reference

12 December 2020

Special issue on lipotoxicity

1 reference

12 December 2020

Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet

1 reference

12 December 2020

Structural alterations to the podocyte are related to proteinuria in type 2 diabetic patients

1 reference

12 December 2020

Suppression of transforming growth factor beta and vascular endothelial growth factor in diabetic nephropathy in rats by a novel advanced glycation end product inhibitor, OPB-9195

1 reference

12 December 2020

Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue

1 reference

12 December 2020

Identifiers

DOI

10.1242/DMM.009266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22773754

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773754%20AND%20SRC:MED&resulttype=core&format=json