(Q36187348)

12 August 2017

First-order rate-determining aggregation mechanism of p53 and its implications (English)

1 reference

12 August 2017

2

Alan R Fersht

1 reference

12 August 2017

GuoZhen Wang

1

1 reference

12 August 2017

language of work or name

English

0 references

publication date

6 August 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

1 reference

12 August 2017

109

1 reference

12 August 2017

34

1 reference

12 August 2017

13590-13595

1 reference

describes a project that uses

12 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3427100/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Allele-specific p53 mutant reactivation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

The amyloid state of proteins in human diseases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Lumry-Eyring nucleated-polymerization model of protein aggregation kinetics. 2. Competing growth via condensation and chain polymerization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Amyloid formation by globular proteins under native conditions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Protein aggregation kinetics, mechanism, and curve-fitting: a review of the literature.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Structural biology of the tumor suppressor p53.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Thermodynamic stability of wild-type and mutant p53 core domain

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

A structural role for metal ions in the "wild-type" conformation of the tumor suppressor protein p53.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

The use of 4-(2-pyridylazo)resorcinol in studies of zinc release from Escherichia coli aspartate transcarbamoylase.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3427100

Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains.

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

Folding of tetrameric p53: oligomerization and tumorigenic mutations induce misfolding and loss of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

Structure, function, and aggregation of the zinc-free form of the p53 DNA binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

A Lumry-Eyring nucleated polymerization model of protein aggregation kinetics: 1. Aggregation with pre-equilibrated unfolding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

Electrocatalytic monitoring of metal binding and mutation-induced conformational changes in p53 at picomole level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1211557109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1211557109

1 reference

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

22869710

1 reference