(Q36188486)

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Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4. (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Mitsuteru Natsuizaka

3

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13 June 2020

author name string

Véronique Giroux

2

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13 June 2020

Mingen Liu

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Andres J Klein-Szanto

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Douglas B Stairs

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Hiroshi Nakagawa

7

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13 June 2020

Kenneth K Wang

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Timothy C Wang

9

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

John P Lynch

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Anil K Rustgi

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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publication date

1 January 2014

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Europe PubMed Central

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12 August 2017

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10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

13

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13 June 2020

24

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13 June 2020

3857-3866

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Barrett esophagus: what a mouse model can teach us about human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Bile acid and inflammation activate gastric cardia stem cells in a mouse model of Barrett-like metaplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Direct reprogramming of mouse fibroblasts to neural progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Mammalian Krüppel-like factors in health and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

The prevalence of Barrett's esophagus in the US: estimates from a simulation model confirmed by SEER data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

The role of Myc-induced protein synthesis in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Facilitating replication under stress: an oncogenic function of MYC?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Intestinal differentiation in metaplastic, nongoblet columnar epithelium in the esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Reflecting on 25 years with MYC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

c-myc amplification is frequent in esophageal adenocarcinoma and correlated with the upregulation of VEGF-A expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

The role of Cdx proteins in intestinal development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Hes1 is a negative regulator of inner ear hair cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

1 October 2017

Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

2 July 2018

Kruppel-like factor 4 contributes to high phosphate-induced phenotypic switching of vascular smooth muscle cells into osteogenic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

2 July 2018

Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

2 July 2018

The ins and outs of notch signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

2 July 2018

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

22 September 2018

Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614677

22 September 2018

Notch signals control the fate of immature progenitor cells in the intestine

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.972875

21 January 2018

Roles of Kruppel-like factor 4 in oesophageal epithelial cells in Barrett's epithelium development

1 reference

https://pubmed.ncbi.nlm.nih.gov/25558829

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/15384101.2014.972875

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25558829%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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