(Q36194069)

12 August 2017

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title

Antisense oligonucleotides as therapeutics for hyperlipidaemias (English)

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12 August 2017

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Rosanne M Crooke

1

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12 August 2017

language of work or name

English

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publication date

1 July 2005

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Expert Opinion on Biological Therapy

12 August 2017

published in

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12 August 2017

volume

5

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12 August 2017

issue

7

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12 August 2017

page(s)

907-917

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Shattuck lecture--cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities.

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Drug treatment of lipid disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Use and monitoring of "statin" lipid-lowering drugs compared with guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Lipid-lowering therapies in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Undertreatment of hyperlipidemia in patients with coronary artery disease and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

The lipid treatment assessment project (L-TAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Progress in antisense technology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Efficiency of antisense oligonucleotide drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

RNAi as a gene therapy approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Tissue disposition of 2'-O-(2-methoxy) ethyl modified antisense oligonucleotides in monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Pharmacokinetics of an anti—human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects*

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4-week study in CD-1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Inhibition of coagulation by a phosphorothioate oligonucleotide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Intracellular assembly of VLDL: two major steps in separate cell compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Very-low-density lipoprotein assembly and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Comparison of apolipoprotein B metabolism in familial defective apolipoprotein B and heterogeneous familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Diagnosis of familial combined hyperlipidemia based on lipid phenotype expression in 32 families: results of a 5-year follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Association of mutations in the apolipoprotein B gene with hypercholesterolemia and the risk of ischemic heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Familial combined hyperlipidemia plasma stimulates protein secretion by HepG2 cells: identification of fibronectin in the differential secretion proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Apolipoprotein B-100 kinetics in visceral obesity: associations with plasma apolipoprotein C-III concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Microsomal triglyceride transfer protein inhibitors: discovery and synthesis of alkyl phosphonates as potent MTP inhibitors and cholesterol lowering agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Metformin reverses fatty liver disease in obese, leptin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Mechanism of action of fibrates on lipid and lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Atorvastatin decreases apolipoprotein C-III in apolipoprotein B-containing lipoprotein and HDL in type 2 diabetes: a potential mechanism to lower plasma triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

Postprandial response to a fat tolerance test in young adults with a paternal history of premature coronary heart disease - the EARS II study (European Atherosclerosis Research Study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.7.907

21 January 2018

Identifiers

DOI

10.1517/14712598.5.7.907

1 reference

12 August 2017

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