(Q45787784)

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Pharmacokinetics of an anti—human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects*

scientific article published on July 1, 1995

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Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

Pharmacokinetics of an anti—human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects* (English)

1 reference

10.1016/0009-9236(95)90071-3

https://api.crossref.org/works/10.1016/0009-9236(95)90071-3

20 June 2024

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pharmacokinetics

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based on heuristic

inferred from title

Oligodeoxyribonucleotides, Antisense

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7628182

20 June 2024

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Saag MS

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Europe PubMed Central

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16 December 2017

http://europepmc.org/abstract/MED/7628182

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R. Zhang

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7628182

20 June 2024

J. Yan

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Europe PubMed Central

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20 June 2024

H. K. Shahinian

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20 June 2024

G. Amin

4

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20 June 2024

Z. Lu

5

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Europe PubMed Central

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20 June 2024

T. Liu

6

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Europe PubMed Central

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20 June 2024

M. S. Saag

7

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Europe PubMed Central

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20 June 2024

Z. Jiang

8

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Europe PubMed Central

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20 June 2024

J. Temsamani

9

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Europe PubMed Central

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20 June 2024

R. R. Martin

10

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Europe PubMed Central

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20 June 2024

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publication date

1 July 1995

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16 December 2017

http://europepmc.org/abstract/MED/7628182

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

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16 December 2017

http://europepmc.org/abstract/MED/7628182

58

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Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

1

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Europe PubMed Central

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16 December 2017

http://europepmc.org/abstract/MED/7628182

44-53

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Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

1

1 reference

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Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus

2

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10.1016/0009-9236(95)90071-3

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Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides

3

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Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus

4

1 reference

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Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells

5

1 reference

10.1016/0009-9236(95)90071-3

https://api.crossref.org/works/10.1016/0009-9236(95)90071-3

20 June 2024

Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues

6

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Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture

7

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Inhibition of human immunodeficiency virus (HIV-1) replication by synthetic oligo-RNA derivatives

8

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Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment

11

1 reference

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Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates

12

1 reference

10.1016/0009-9236(95)90071-3

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Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages

13

1 reference

10.1016/0009-9236(95)90071-3

https://api.crossref.org/works/10.1016/0009-9236(95)90071-3

20 June 2024

GEM 91--an antisense oligonucleotide phosphorothioate as a therapeutic agent for AIDS

17

1 reference

10.1016/0009-9236(95)90071-3

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Antisense oligodeoxynucleotide phosphorothioate complementary to Gag mRNA blocks replication of human immunodeficiency virus type 1 in human peripheral blood cells

18

1 reference

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Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

19

1 reference

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Pharmacokinetics, biodistribution, and stability of capped oligodeoxynucleotide phosphorothioates in mice

21

1 reference

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Molecular Pharmacology

24

45

932

author name string

Sands H.

publication date

1994

1 reference

10.1016/0009-9236(95)90071-3

https://api.crossref.org/works/10.1016/0009-9236(95)90071-3

20 June 2024

Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.

25

1 reference

10.1016/0009-9236(95)90071-3

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Large-scale synthesis, purification, and analysis of oligodeoxynucleotide phosphorothioates

26

1 reference

10.1016/0009-9236(95)90071-3

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Drug Metabolism and Disposition

31

20

113

author name string

Zhang R.

publication date

1992

1 reference

10.1016/0009-9236(95)90071-3

https://api.crossref.org/works/10.1016/0009-9236(95)90071-3

20 June 2024

Identifiers

10.1016/0009-9236(95)90071-3

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 December 2017

http://europepmc.org/abstract/MED/7628182

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