(Q36200224)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Cytokine-mediated β-cell damage in PARP-1-deficient islets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Teresa Andreone

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Katherine J Hughes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Polly A Hansen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

John A Corbett

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

publication date

24 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Endocrinology and Metabolism

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

E172-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

30 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3431132/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 October 2017

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1 October 2017

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SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus

1 October 2017

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1 October 2017

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Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines

1 October 2017

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Necrotic death as a cell fate

1 October 2017

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Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1

1 October 2017

1 reference

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

1 October 2017

1 reference

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PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

1 October 2017

1 reference

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Type 1 database mellitus: an inflammatory disease of the islet.

1 October 2017

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Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications.

1 October 2017

1 reference

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Apoptotic signal transduction pathways in diabetes

1 October 2017

1 reference

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Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1.

1 October 2017

1 reference

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Poly(ADP-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts

1 October 2017

1 reference

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Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells

1 October 2017

1 reference

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Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

1 October 2017

1 reference

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Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

1 October 2017

1 reference

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Potential role of PKR in double-stranded RNA-induced macrophage activation

1 October 2017

1 reference

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Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.

1 October 2017

1 reference

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Discovering new ADP-ribose polymer cycles: protecting the genome and more

1 October 2017

1 reference

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Nitric oxide-induced damage to mtDNA and its subsequent repair

1 October 2017

1 reference

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The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase

1 October 2017

1 reference

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Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

1 October 2017

1 reference

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PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

1 October 2017

1 reference

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pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans

1 October 2017

1 reference

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A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues

1 October 2017

1 reference

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Poly(ADP-ribose) polymerase in the cellular response to DNA damage, apoptosis, and disease

1 October 2017

1 reference

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Nicotinamide in type 1 diabetes. Mechanism of action revisited.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Double-stranded RNA-induced inducible nitric-oxide synthase expression and interleukin-1 release by murine macrophages requires NF-kappaB activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Evidence for involvement of the proteasome complex (26S) and NFkappaB in IL-1beta-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

DNA damage and nitric oxide

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Cytokines, nitric oxide and insulin secreting cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1 beta indicate a perturbation in the mitochondrial function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Streptozotocin interactions with pancreatic beta cells and the induction of insulin-dependent diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Potent beta-cell protection in vitro by an isoquinolinone-derived PARP inhibitor.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Interrelationship of changes in islet nicotine adeninedinucleotide, insulin secretion, and cell viability induced by interleukin-1 beta

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Toxicity determined in vitro by morphological alterations and neutral red absorption

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

ERK activation is required for double-stranded RNA- and virus-induced interleukin-1 expression by macrophages

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431132

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152%2FAJPENDO.00055.2012

Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans

21 January 2018

1 reference

12 December 2020

DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin

1 reference

12 December 2020

Mechanisms of nitrosourea-induced beta-cell damage. Activation of poly (ADP-ribose) synthetase and cellular distribution

1 reference

12 December 2020

Isolation of islets of Langerhans from rodent pancreas

1 reference

12 December 2020

Toxicity of chemically generated nitric oxide towards pancreatic islet cells can be prevented by nicotinamide

1 reference

12 December 2020

Islet cell DNA is a target of inflammatory attack by nitric oxide

1 reference

12 December 2020

Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets

1 reference

12 December 2020

Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans

1 reference

12 December 2020

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

1 reference

12 December 2020

Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation

1 reference

12 December 2020

Newly discovered anti-inflammatory properties of the benzamides and nicotinamides

1 reference

12 December 2020

10.1152/AJPENDO.00055.2012

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

22535743

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22535743%20AND%20SRC:MED&resulttype=core&format=json