(Q36204415)

12 August 2017

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title

Dysregulation of T-cell function in the elderly : scientific basis and clinical implications (English)

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12 August 2017

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Tamas Fulop

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Graham Pawelec

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Graham Pawelec

6

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Anis Larbi

2

object named as

Anis Larbi

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12 August 2017

Tamas Fulop

1

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12 August 2017

Anders Wikby

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12 August 2017

Eugenio Mocchegiani

4

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12 August 2017

Katsuiku Hirokawa

5

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12 August 2017

1 January 2005

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12 August 2017

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22

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7

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12 August 2017

589-603

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https://scigraph.springernature.com/pub.10.2165/00002512-200522070-00005

12 August 2017

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cites work

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

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12 December 2020

Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities

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12 December 2020

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12 December 2020

Nutrition and immunity in the elderly: modification of immune responses with nutritional treatments

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12 December 2020

Clinical relevance of age-related immune dysfunction

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12 December 2020

Immunosenescence: impact in the young as well as the old?

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12 December 2020

Aging: a theory based on free radical and radiation chemistry

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12 December 2020

Telomere shortening in T cells correlates with Alzheimer's disease status.

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12 December 2020

Nutritional formula enhanced immune function and reduced days of symptoms of upper respiratory tract infection in seniors.

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12 December 2020

Immunity and aging: the enemy within?

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12 December 2020

Zinc, metallothioneins, immune responses, survival and ageing

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12 December 2020

Understanding the mechanism of the age-change of thymic function to promote T cell differentiation

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12 December 2020

Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space

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12 December 2020

Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse

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12 December 2020

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

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12 December 2020

Quantitative intracellular cytokine measurement: age-related changes in proinflammatory cytokine production

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12 December 2020

Hormones and immune function: implications of aging

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12 December 2020

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

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12 December 2020

Expansion of peripheral CD8+ T cells in patients with coronary artery disease: relation to cytomegalovirus infection

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12 December 2020

Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human cd4+ tcr2+ cultured T cell clones

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12 December 2020

Relationship between the response to influenza vaccination and the nutritional status in institutionalized elderly subjects

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12 December 2020

Inflamm-aging. An evolutionary perspective on immunosenescence

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12 December 2020

Immune response during disease and recovery in the elderly

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12 December 2020

Hemopoiesis in healthy old people and centenarians: well-maintained responsiveness of CD34+ cells to hemopoietic growth factors and remodeling of cytokine network.

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12 December 2020

Immune Parameters in a Longitudinal Study of a Very Old Population of Swedish People: A Comparison Between Survivors and Nonsurvivors

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12 December 2020

Immunosurveillance and cancer: epidemiologic observations

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12 December 2020

The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial

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12 December 2020

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12 December 2020

Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging

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12 December 2020

Epidemiology and unique aspects of aging and infectious diseases

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12 December 2020

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12 December 2020

Cancer immunotherapy: a treatment for the masses

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12 December 2020

The relation between immunology, nutrition and disease in elderly people

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12 December 2020

Elderly Humans Show Prolonged In Vivo Inflammatory Activity during Pneumococcal Infections

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12 December 2020

Aging and innate immune cells

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12 December 2020

Age-associated changes in thymopoiesis.

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12 December 2020

Plasma membrane microdomains: organization, function and trafficking

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12 December 2020

Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence

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12 December 2020

Neuroinflammation and the genetics of Alzheimer's disease: the search for a pro-inflammatory phenotype

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12 December 2020

Centenarians as a model for healthy aging

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12 December 2020

The relationship between nutrition, infection, and immunity

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12 December 2020

Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

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12 December 2020

Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines

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12 December 2020

Nutritional strategies to boost immunity and prevent infection in elderly individuals

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12 December 2020

Tumor necrosis factor alpha augments amyloid beta protein (25-35) induced apoptosis in human cells

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12 December 2020

Immunohistochemical detection of macrophages and T lymphocytes in atherosclerotic lesions of cholesterol-fed rabbits

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12 December 2020

The immunological synapse.

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12 December 2020

Anemia, cancer, and aging

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12 December 2020

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12 December 2020

Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes

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12 December 2020

Zinc, infections and immunosenescence.

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12 December 2020

Trends in Heart Failure Incidence and Survival in a Community-Based Population

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12 December 2020

Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats

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12 December 2020

Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply

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12 December 2020

Atherosclerosis as an autoimmune disease: an update

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12 December 2020

Role of cytomegalovirus in the T cell changes seen in elderly individuals

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12 December 2020

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12 December 2020

TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs

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12 December 2020

Is immunosenescence infectious?

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12 December 2020

NK and NKT cell functions in immunosenescence

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12 December 2020

Retardation of the age-associated decline of immune functions in aging rats under dietary restriction and daily physical exercise

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12 December 2020

T-cell activation through the antigen receptor. Part 2: role of signaling cascades in T-cell differentiation, anergy, immune senescence, and development of immunotherapy.

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12 December 2020

A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity

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12 December 2020

Inflammation in atherosclerosis

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12 December 2020

Ageing is associated with a prolonged fever response in human endotoxemia

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12 December 2020

Autoimmune and inflammatory mechanisms in atherosclerosis

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12 December 2020

Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?

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12 December 2020

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

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12 December 2020

Benefits of influenza vaccination for low-, intermediate-, and high-risk senior citizens

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12 December 2020

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

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12 December 2020

Immunostimulant patch enhances immune responses to influenza virus vaccine in aged mice

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12 December 2020

The unexpected contribution of immunosenescence to the leveling off of cancer incidence and mortality in the oldest old.

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12 December 2020

The variations during the circadian cycle of liver CD1d-unrestricted NK1.1+TCR gamma/delta+ cells lead to successful ageing. Role of metallothionein/IL-6/gp130/PARP-1 interplay in very old mice

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12 December 2020

Therapeutic application of zinc in human immunodeficiency virus against opportunistic infections

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12 December 2020

Serum IL-6 level and the development of disability in older persons

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12 December 2020

Immunodeficiency of aging

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12 December 2020

Myocyte growth and cardiac repair

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12 December 2020

Refining the telomere-telomerase hypothesis of aging and cancer.

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12 December 2020

Estrogen replacement, aging, and cell-mediated immunity after injury

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12 December 2020

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

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12 December 2020

Morbidity does not influence the T-cell immune risk phenotype in the elderly: findings in the Swedish NONA Immune Study using sample selection protocols

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12 December 2020

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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12 December 2020

Combined grafting of bone marrow and thymus, and sequential multiple thymus graftings in various strains of mice. The effect on immune functions and life span

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12 December 2020

Protein-energy undernutrition among elderly hospitalized patients: a prospective study

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12 December 2020

The expression and roles of Toll-like receptors in the biology of the human neutrophil.

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12 December 2020

Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors

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12 December 2020

Signal transduction and functional changes in neutrophils with aging.

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12 December 2020

Is atherosclerosis an immunologically mediated disease?

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12 December 2020

Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation

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12 December 2020

Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals

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12 December 2020

Therapeutic vaccines for chronic infections

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12 December 2020

Altered T cell signalling in ageing

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12 December 2020

Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T cells

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12 December 2020

10.2165/00002512-200522070-00005

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

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