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12 February 2020

1 reference

26 October 2022

The impact of interferon lambda 3 gene polymorphism on natural course and treatment of hepatitis C (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

1 July 2020

single-nucleotide polymorphism

1 reference

14 September 2019

1 reference

3 November 2019

1 reference

20 November 2019

1

1 reference

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12 February 2020

Gaetano Serviddio

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4

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12 February 2020

2

G Vendemiale

1 reference

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12 February 2020

3

E Altomare

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12 February 2020

language of work or name

1 reference

27 August 2012

12 references

23 March 2019

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30 June 2019

14 September 2019

3 November 2019

20 November 2019

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12 February 2020

1 July 2020

22 October 2022

25 October 2022

26 October 2022

Clinical and Developmental Immunology

12 references

23 March 2019

21 March 2019

19 June 2019

30 June 2019

14 September 2019

3 November 2019

20 November 2019

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12 February 2020

1 July 2020

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2012

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12 February 2020

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Creative Commons Attribution 3.0 Unported

12 February 2020

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cites work

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IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study

1 October 2017

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1 October 2017

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IL28B genotype effects during early treatment with peginterferon and ribavirin in difficult-to-treat hepatitis C virus infection

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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A polymorphism in IL28B distinguishes exposed, uninfected individuals from spontaneous resolvers of HCV infection.

1 October 2017

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IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection

1 October 2017

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Boceprevir for previously treated chronic HCV genotype 1 infection

1 October 2017

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1 October 2017

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1 October 2017

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Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms

1 October 2017

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Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy

1 October 2017

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1 October 2017

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Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIV-positive patients with acute and chronic hepatitis C.

1 October 2017

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IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway

1 October 2017

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IL28B polymorphism is associated with both side effects and clearance of hepatitis C during interferon-alpha therapy.

1 October 2017

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1 October 2017

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IL28B SNP rs8099917 is strongly associated with pegylated interferon-α and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients

1 October 2017

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IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

1 October 2017

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1 October 2017

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Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection.

1 October 2017

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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

1 October 2017

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1 October 2017

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Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

1 October 2017

1 reference

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

1 October 2017

1 reference

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IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

1 October 2017

1 reference

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Human interferon-lambda3 is a potent member of the type III interferon family.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Treatment predictors of a sustained virologic response in hepatitis B and C.

1 October 2017

1 reference

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Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Id2 leaves the chromatin of the E2F4-p130-controlled c-myc promoter during hepatocyte priming for liver regeneration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Lambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Review article: chronic hepatitis C--natural history and cofactors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Global epidemiology of hepatitis C virus infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Lambda interferon inhibits hepatitis B and C virus replication

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

IL-28, IL-29 and their class II cytokine receptor IL-28R

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Current and future treatment of hepatitis C.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Preclinical and clinical development of pegylated interferon-lambda 1 in chronic hepatitis C.

1 October 2017

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Recipient IL28B polymorphism is an important independent predictor of posttransplant diabetes mellitus in liver transplant patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Meta-analysis: IL28B polymorphisms predict sustained viral response in HCV patients treated with pegylated interferon-α and ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Association between IL28B polymorphisms and first-phase viral load decrease in chronic hepatitis C virus-infected patients treated with peginterferon alfa-2b/ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Association between the IL28B genotype and hepatitis C viral kinetics in the early days of treatment with pegylated interferon plus ribavirin in HIV/HCV co-infected patients with genotype 1 or 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatitis C virus kinetics in chimeric mice during antiviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Serum level of IP-10 increases predictive value of IL28B polymorphisms for spontaneous clearance of acute HCV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Do lambda-IFNs IL28A and IL28B act on human natural killer cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F849373

Hepatitis C viral load, genotype 3 and interleukin-28B CC genotype predict mortality in HIV and hepatitis C-coinfected individuals.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

IL28B CC genotype is associated with higher all-cause mortality in antiretroviral-treated HIV-infected patients.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Association between interleukin-28B-related genetic variants and liver histopathology differs between hepatitis C virus genotypes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV–hepatitis C virus-coinfected patients with prior nonresponse or relapse

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433716

Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22966241

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2012/849373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

22966241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22966241%20AND%20SRC:MED&resulttype=core&format=json