(Q36209954)

12 August 2017

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title

Theoretical models of selection and mutation on quantitative traits (English)

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12 August 2017

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1 reference

Toby Johnson

1

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author name string

Nick Barton

series ordinal

2

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PMCID

1569515

12 August 2017

language of work or name

English

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publication date

1 July 2005

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Philosophical Transactions of the Royal Society B

12 August 2017

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12 August 2017

360

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12 August 2017

1411-1425

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12 August 2017

1459

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The genetics of adaptation: a reassessment

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The Genetic Covariance between Characters Maintained by Pleiotropic Mutations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Excursions along the Interface between Disruptive and Stabilizing Selection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Genotype-environment interactions and the maintenance of polygenic variation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The effects of intraspecific competition and stabilizing selection on a polygenic trait

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Polygenic variation maintained by balancing selection: pleiotropy, sex-dependent allelic effects and G x E interactions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Scaling of mutational effects in models for pleiotropy.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The allelic architecture of human disease genes: common disease-common variant... or not?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Functional profiling of the Saccharomyces cerevisiae genome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropic model of maintenance of quantitative genetic variation at mutation-selection balance.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

A comprehensive review of genetic association studies

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

MULTIFACTORIAL GENETICSUNDERSTANDING QUANTITATIVE GENETIC VARIATION

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Is the population size of a species relevant to its evolution?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Large upward bias in estimation of locus-specific effects from genomewide scans

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

How closely correlated are molecular and quantitative measures of genetic variation? A meta-analysis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Chance and necessity: the evolution of morphological complexity and diversity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Detecting the undetected: estimating the total number of loci underlying a quantitative trait

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Perspective: Evolutionary developmental biology and the problem of variation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Spontaneous mutational effects on reproductive traits of arabidopsis thaliana

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete-scute complex are associated with variation in bristle number in Drosophila melanogaster.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Evolution of genetic variability and the advantage of sex and recombination in changing environments.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

An analysis of polygenes affecting wing shape on chromosome 3 in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Terumi Mukai and the riddle of deleterious mutation rates

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The changes in genetic and environmental variance with inbreeding in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

High genomic deleterious mutation rates in hominids

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Two sites in the Delta gene region contribute to naturally occurring variation in bristle number in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Rates of spontaneous mutation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Comparing mutational variabilities.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

A genetic map of quantitative trait loci for body weight in the mouse.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

A stochastic model concerning the maintenance of genetic variability in quantitative characters

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Molecular population genetics of the alcohol dehydrogenase gene region of Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Evolutionary quantitative genetics: how little do we know?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropic models of quantitative variation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Increased selection response in larger populations. II. Selection for ethanol vapor resistance in Drosophila melanogaster at two population sizes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Efficiency of marker-assisted selection in the improvement of quantitative traits.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Comparing evolvability and variability of quantitative traits

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

How small are the smallest selectable domains of form?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Effects of P element insertions on quantitative traits in Drosophila melanogaster

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variation at mutation-selection balance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Average dominance for polygenes: drawbacks of regression estimates.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Nature of deleterious mutation load in Drosophila.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropic models of polygenic variation, stabilizing selection, and epistasis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropic stabilizing selection limits the number of polymorphic loci to at most the number of characters

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The quantitative genetic consequences of pleiotropy under stabilizing and directional selection

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Frequency- and density-dependent selection on a quantitative character.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Two steps forward, one step back: the pleiotropic effects of favoured alleles.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Joint effects of pleiotropic selection and stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Evolution in vitro: analysis of a lineage of ribozymes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Deleterious mutations and the evolution of sex.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

Pleiotropy and the preservation of perfection

22 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

22 September 2018

https://api.crossref.org/works/10.1098%2FRSTB.2005.1667

A pleiotropic nonadditive model of variation in quantitative traits

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569515

The Strength of Phenotypic Selection in Natural Populations

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSTB.2005.1667

The approach to mutation-selection balance in an infinite asexual population, and the evolution of mutation rates

21 January 2018

1 reference

12 December 2020

Clines in polygenic traits

1 reference

12 December 2020

One sequence, two ribozymes: implications for the emergence of new ribozyme folds

1 reference

12 December 2020

ADAPTATION AND THE COST OF COMPLEXITY

1 reference

12 December 2020

The maintenance of genetic variability by mutation in a polygenic character with linked loci

1 reference

12 December 2020

Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability

1 reference

12 December 2020

Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation

1 reference

12 December 2020

Hybridization of bird species

1 reference

12 December 2020

Quantitative genetic variability maintained by mutation-stabilizing selection balance: sampling variation and response to subsequent directional selection

1 reference

12 December 2020

THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS

1 reference

12 December 2020

THE POPULATION GENETICS OF ADAPTATION: THE DISTRIBUTION OF FACTORS FIXED DURING ADAPTIVE EVOLUTION.

1 reference

12 December 2020

PERSPECTIVE: COMPLEX ADAPTATIONS AND THE EVOLUTION OF EVOLVABILITY.

1 reference

12 December 2020

PERSPECTIVE: SPONTANEOUS DELETERIOUS MUTATION.

1 reference

12 December 2020

INBREEDING AND ITS FITNESS EFFECTS IN AN INSULAR POPULATION OF SONG SPARROWS (MELOSPIZA MELODIA).

1 reference

12 December 2020

The rate of polygenic mutation

1 reference

12 December 2020

Heritable variation and heterozygosity under a balance between mutations and stabilizing selection

1 reference

12 December 2020

The maintenance of polygenic variation through a balance between mutation and stabilizing selection

1 reference

12 December 2020

Variation for metrical characters in Drosophila populations. II. Natural selection

1 reference

12 December 2020

The founder effect and response to artificial selection

1 reference

12 December 2020

The Genetic Variance Maintained by Pleiotropic Mutation

1 reference

12 December 2020

IS THE POPULATION SIZE OF A SPECIES RELEVANT TO ITS EVOLUTION?

1 reference

12 December 2020

THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS.

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2005.1667

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

1569515