(Q36217485)

12 August 2017

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title

Building specificity with nonspecific RNA-binding proteins (English)

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12 August 2017

2

Juan Valcárcel

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12 August 2017

Ravinder Singh

1

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12 August 2017

publication date

1 August 2005

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Nature Structural & Molecular Biology

12 August 2017

published in

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12 August 2017

volume

12

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12 August 2017

issue

8

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12 August 2017

page(s)

645-653

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https://scigraph.springernature.com/pub.10.1038/nsmb961

12 August 2017

exact match

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Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor

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Exon Identity Established through Differential Antagonism between Exonic Splicing Silencer-Bound hnRNP A1 and Enhancer-Bound SR Proteins

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hnRNP A1 controls HIV-1 mRNA splicing through cooperative binding to intron and exon splicing silencers in the context of a conserved secondary structure

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A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels

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The SR protein SRp38 represses splicing in M phase cells

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Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock

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Signal-dependent regulation of splicing via phosphorylation of Sam68

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Sex lethal and U2 small nuclear ribonucleoprotein auxiliary factor (U2AF65) recognize polypyrimidine tracts using multiple modes of binding

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Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein

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Structure of the Y14-Magoh core of the exon junction complex

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A novel mode of RBD-protein recognition in the Y14–Mago complex

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Crystal structure of theDrosophilaMago nashi–Y14 complex

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The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

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Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP

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A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer

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Crystal structure of the human nuclear cap binding complex

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Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA

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U2AF homology motifs: protein recognition in the RRM world

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A molecular link between SR protein dephosphorylation and mRNA export

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Nuclear export and retention signals in the RS domain of SR proteins

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Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing

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A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.

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Analysis of the functional specificity of RS domains in vivo

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Pre-mRNA splicing in the absence of an SR protein RS domain

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Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

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A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly

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Structuring of the 3' splice site by U2AF65.

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Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.

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Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

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SR proteins preferentially associate with mRNAs in the nucleus and facilitate their export to the cytoplasm

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SR splicing factors serve as adapter proteins for TAP-dependent mRNA export

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A novel role for shuttling SR proteins in mRNA translation

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KH domain: one motif, two folds

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Protein and RNA dynamics play key roles in determining the specific recognition of GU-rich polyadenylation regulatory elements by human Cstf-64 protein

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Systematic identification and analysis of exonic splicing silencers.

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Predictive identification of exonic splicing enhancers in human genes

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Identification of a new class of exonic splicing enhancers by in vivo selection

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The spliceosome: no assembly required?

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Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins

31 March 2020

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Splicing regulation in Drosophila sex determination.

31 March 2020

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A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy

31 March 2020

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Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon.

31 March 2020

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Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors

31 March 2020

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Intron recognition comes of AGe

31 March 2020

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Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected]

31 March 2020

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Involvement of SR proteins in mRNA surveillance

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB961

1 reference

12 August 2017

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