(Q36219326)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Teresa Lambe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Fabienne Mackay

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Elissa K. Deenick

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Stuart Tangye

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Chris Goodnow

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Katrina L Randall

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Andy L Johnson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Bebhinn Treanor

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Edyta Kucharska

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Heather Domaschenz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Belinda Whittle

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Lina E Tze

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tanya L Crockford

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tiphaine Bouriez-Jones

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Duncan Alston

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jason G Cyster

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Michael J Lenardo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tyani D Chan

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tahra Camidge

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Robert Brink

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Carola G Vinuesa

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Facundo D Batista

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Richard J Cornall

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

8 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

1283-1291

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

Combined immunodeficiency associated with DOCK8 mutations

12 February 2020

cites work

1 reference

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Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor

1 October 2017

1 reference

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Primary B cell immunodeficiencies: comparisons and contrasts

1 October 2017

1 reference

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SAP-controlled T-B cell interactions underlie germinal centre formation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Common variable immunodeficiency: a new look at an old disease.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Deconstructing common variable immunodeficiency by genetic analysis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

High affinity germinal center B cells are actively selected into the plasma cell compartment.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

An antibody-deficiency syndrome due to mutations in the CD19 gene

1 October 2017

1 reference

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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

CZH proteins: a new family of Rho-GEFs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

TACI is mutant in common variable immunodeficiency and IgA deficiency

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Extrafollicular antibody responses

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

X-ray snapshots of the maturation of an antibody response to a protein antigen

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Opening a window on thymic positive selection: developmental changes in the influence of cosignaling by integrins and CD28 on selection events induced by TCR engagement

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesis

1 October 2017

1 reference

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A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus

1 October 2017

1 reference

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Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

1 October 2017

1 reference

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Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes

1 October 2017

1 reference

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Antigen-induced B-cell death and elimination during germinal-centre immune responses

29 June 2018

1 reference

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Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts.

29 June 2018

1 reference

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Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

22 September 2018

1 reference

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The EUROclass trial: defining subgroups in common variable immunodeficiency.

22 September 2018

1 reference

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FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

The physiologic role of CD19 cytoplasmic tyrosines

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Integrin-mediated long-term B cell retention in the splenic marginal zone.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437189

Prolyl 4-hydroxylation regulates Argonaute 2 stability

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1820

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1820

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.1820

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

21 January 2018

1 reference

12 December 2020

Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk

1 reference

12 December 2020

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

1 reference

12 December 2020

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

1 reference

12 December 2020

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

1 reference

12 December 2020

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1820

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19898472%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19898472

1 reference