Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36223221)
Watch
English
Manganese-induced toxicity in normal and human B lymphocyte cell lines containing a homozygous mutation in parkin.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
Manganese-induced toxicity in normal and human B lymphocyte cell lines containing a homozygous mutation in parkin
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
main subject
homozygosity
1 reference
based on heuristic
inferred from title
author
Balakrishnan Ganapathy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Andrew J Ghio
series ordinal
3
object named as
Andrew J Ghio
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Jerome A Roth
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
publication date
26 July 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Toxicology in Vitro
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
26
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
1143-1149
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
cites work
Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Are there common biochemical and molecular mechanisms controlling manganism and parkisonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkinson's disease: from monogenic forms to genetic susceptibility factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Molecular basis of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Clinical genetics of Parkinson's disease and related disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
p38 MAPK and MSK1 mediate caspase-8 activation in manganese-induced mitochondria-dependent cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Homeostatic and toxic mechanisms regulating manganese uptake, retention, and elimination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin suppresses the expression of monoamine oxidases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Changes in the brain mitochondrial proteome of male Sprague-Dawley rats treated with manganese chloride
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin attenuates manganese-induced dopaminergic cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Part I: parkin-associated proteins and Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Functional association of the parkin gene promoter with idiopathic Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Manganese-induced apoptosis in PC12 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Dopamine transporter density is decreased in parkinsonian patients with a history of manganese exposure: what does it mean?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Parkin and Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Manganese and calcium transport in mitochondria: implications for manganese toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Effects from environmental Mn exposures: a review of the evidence from non-occupational exposure studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Manganese induces apoptosis of human B cells: caspase-dependent cell death blocked by bcl-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
1 October 2017
The case for manganese interaction with mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Association study of Parkin gene polymorphisms with idiopathic Parkinson disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Oxidative stress involves in astrocytic alterations induced by manganese
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Mn2+ sequestration by mitochondria and inhibition of oxidative phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
29 June 2018
Mitochondrial defect and PGC-1α dysfunction in parkin-associated familial Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
22 September 2018
Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
22 September 2018
Genotoxic and cytotoxic effects of manganese chloride in cultured human lymphocytes treated in different phases of cell cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
22 September 2018
Autosomal recessive juvenile parkinsonism Cys212Tyr mutation in parkin renders lymphocytes susceptible to dopamine- and iron-mediated apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438308
retrieved
22 September 2018
Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22841634
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22841634
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Association of codon 167 Ser/Asn heterozygosity in the parkin gene with sporadic Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22841634
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Manganese-induced rat pheochromocytoma (PC12) cell death is independent of caspase activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22841634
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIV.2012.07.005
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMC publication ID
3438308
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
22841634
1 reference
stated in
Europe PubMed Central
PMC publication ID
3438308
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22841634%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit