(Q36224671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

1 reference

1 reference

1 reference

host translation inhibitor nsp1 [SARS-Cov]

0 references

Envelope small membrane protein [SARS-Cov]

0 references

author

Jose M Jiménez-Guardeño

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Raul Fernandez-Delgado

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Stanley Perlman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Luis Enjuanes

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

3

Jose L Nieto-Torres

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

4

Marta L DeDiego

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Carlos Castaño-Rodriguez

5

object named as

Carlos Castaño-Rodriguez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Jose A Regla-Nava

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

29 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

e1005215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

28 February 2020

copyright license

start time

29 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 October 2017

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1 October 2017

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1 October 2017

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Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival

1 October 2017

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Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

1 October 2017

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The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokines

1 October 2017

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Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge.

1 October 2017

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Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.

1 October 2017

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Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein

1 October 2017

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The role of flexibility and conformational selection in the binding promiscuity of PDZ domains

1 October 2017

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1 October 2017

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Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 October 2017

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Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA.

1 October 2017

1 reference

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Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids.

1 October 2017

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Template-based protein structure modeling using the RaptorX web server.

1 October 2017

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SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

1 October 2017

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Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses

1 October 2017

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Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein

1 October 2017

1 reference

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Evolved variants of the membrane protein can partially replace the envelope protein in murine coronavirus assembly

1 October 2017

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The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis.

1 October 2017

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T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice

1 October 2017

1 reference

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Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

1 October 2017

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SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism

1 October 2017

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Exacerbated innate host response to SARS-CoV in aged non-human primates

1 October 2017

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Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

1 October 2017

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A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

1 October 2017

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Coronaviruses post-SARS: update on replication and pathogenesis

1 October 2017

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Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses

1 October 2017

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The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

1 October 2017

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Flavivirus NS5 associates with host-cell proteins zonula occludens-1 (ZO-1) and regulating synaptic membrane exocytosis-2 (RIMS2) via an internal PDZ binding mechanism

1 October 2017

1 reference

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MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

1 October 2017

1 reference

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A specificity map for the PDZ domain family

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters

1 October 2017

1 reference

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Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.

1 October 2017

1 reference

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Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Detection of group 1 coronaviruses in bats in North America

1 October 2017

1 reference

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Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Severe acute respiratory syndrome coronavirus accessory protein 6 is a virion-associated protein and is released from 6 protein-expressing cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Act globally, think locally: systems biology addresses the PDZ domain

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Model of a putative pore: the pentameric alpha-helical bundle of SARS coronavirus E protein in lipid bilayers.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Molecular diversity of coronaviruses in bats.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Bats are natural reservoirs of SARS-like coronaviruses

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Early enhanced expression of interferon-inducible protein-10 (CXCL-10) and other chemokines predicts adverse outcome in severe acute respiratory syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Can successful vaccines teach us how to induce efficient protective immune responses?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Animal coronavirus vaccines: lessons for SARS.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Secondary structure and function of the 5'-proximal region of the equine arteritis virus RNA genome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Coronavirus as a possible cause of severe acute respiratory syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

The small envelope protein E is not essential for murine coronavirus replication

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

PDZ domains: structural modules for protein complex assembly

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Efficacy of a transmissible gastroenteritis coronavirus with an altered ORF-3 gene.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Targeted recombination demonstrates that the spike gene of transmissible gastroenteritis coronavirus is a determinant of its enteric tropism and virulence.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

RNA recombination in a coronavirus: recombination between viral genomic RNA and transfected RNA fragments

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

The severe acute respiratory syndrome coronavirus 3a is a novel structural protein.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Antibody responses to individual proteins of SARS coronavirus and their neutralization activities.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Tracing SARS-coronavirus variant with large genomic deletion

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Differentiation of a Vero cell adapted porcine epidemic diarrhea virus from Korean field strains by restriction fragment length polymorphism analysis of ORF 3

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4626112

Two Amino Acid Changes at the N-Terminus of Transmissible Gastroenteritis Coronavirus Spike Protein Result in the Loss of Enteric Tropism

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005215

ORF8a of SARS-CoV forms an ion channel: Experiments and molecular dynamics simulations

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1005215

Evidence for variable rates of recombination in the MHV genome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26513244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specific for CD4+ and CD8+ T cells promote cellular immune responses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26513244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of specificity and promiscuity of PDZ domain interactions through their dynamic behavior

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26513244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1005215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26513244%20AND%20SRC:MED&resulttype=core&format=json