(Q36237414)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Sphingolipid content of human adipose tissue: relationship to adiponectin and insulin resistance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

N-tetracosanoylsphingosine

4 February 2020

main subject

1 reference

Agnieszka Blachnio-Zabielska

ChEBI release 2020-05-28

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Christina Koutsari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Tamara Tchkonia

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Michael D Jensen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

publication date

7 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

2341-2347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

4 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Sphingolipids function as downstream effectors of a fungal PAQR.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Aging up-regulates expression of inflammatory mediators in mouse adipose tissue

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Abdominal obesity and metabolic syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Inflammation, stress, and diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Adipose tissue and its relation to inflammation: the role of adipokines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Inflammation: the link between insulin resistance, obesity and diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Radiation and ceramide-induced apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

A quick, reliable, and automated method for fat cell sizing

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

The sphingomyelin-signaling pathway in skeletal muscles and its role in regulation of glucose uptake.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Sphingolipids in mammalian cell signalling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Transcriptional repression of the C/EBP-alpha and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulations is coordinate and independent of protein synthesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443533

The quantitative relationship between "the metabolic syndrome" and abdominal obesity in women

22 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Molecular mechanisms of insulin resistance and the role of the adipocyte

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappaB/JNK kinase and cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Ceramide mediates TNF-α-induced insulin resistance on GLUT4 gene expression in brown adipocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Ceramide metabolism is affected by obesity and diabetes in human adipose tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Measurement of abdominal and visceral fat with computed tomography and dual-energy x-ray absorptiometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

Sphingomyelinase assay using radiolabeled substrate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2012.126

31 March 2020

Identifiers

DOI

10.1038/OBY.2012.126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

22677645

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22677645%20AND%20SRC:MED&resulttype=core&format=json