(Q35208833)

7 August 2017

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title

Radiation and ceramide-induced apoptosis (English)

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7 August 2017

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Richard Kolesnick

1

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PubMed ID

12947396

7 August 2017

Zvi Fuks

series ordinal

2

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PubMed ID

12947396

7 August 2017

language of work or name

English

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publication date

1 September 2003

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7 August 2017

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7 August 2017

22

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7 August 2017

5897-5906

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7 August 2017

37

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206702

7 August 2017

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cites work

A novel cytoplasmic domain of the p55 tumor necrosis factor receptor initiates the neutral sphingomyelinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation

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7 January 2021

Ceramide enables fas to cap and kill.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Sphingolipids are potential heat stress signals in Saccharomyces

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Enzymes of sphingolipid metabolism: from modular to integrative signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Sensing and repairing DNA double-strand breaks

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae

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7 January 2021

Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.

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7 January 2021

Compartmentalization of ceramide signaling: physical foundations and biological effects

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7 January 2021

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Human vascular endothelial cells are a rich and regulatable source of secretory sphingomyelinase. Implications for early atherogenesis and ceramide-mediated cell signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism

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7 January 2021

Cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cerebellar granule cells developing in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ceramide mediates tumor necrosis factor effects on P450-aromatase activity in cultured granulosa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Structural organization and complete nucleotide sequence of the gene encoding human acid sphingomyelinase (SMPD1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Fatty acyl-Co A: sphingosine acyltransferase in bovine brain mitochondria: its solubilization and reconstitution onto the membrane lipid liposomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

How cells handle cholesterol.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Signal transduction through lipid second messengers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Sphingosine 1-phosphate as a therapeutic agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Tyrosine phosphorylation is a mandatory proximal step in radiation-induced activation of the protein kinase C signaling pathway in human B-lymphocyte precursors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Heat-induced elevation of ceramide in Saccharomyces cerevisiae via de novo synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Ceramide activates the stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Kinase suppressor of Ras is ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206702

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206702

1 reference

7 August 2017

1 reference

PubMed ID

12947396