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The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.
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PMC publication ID
3447739
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802261%20AND%20SRC:MED&resulttype=core&format=json
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8 February 2020
title
The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment
(English)
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PMC publication ID
3447739
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8 February 2020
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Chuay Yeng Koo
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2
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3447739
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8 February 2020
Eric W-F Lam
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7
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3447739
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8 February 2020
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Natalia de Olano
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3447739
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8 February 2020
Lara J Monteiro
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3
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8 February 2020
Paola H Pinto
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4
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8 February 2020
Ana R Gomes
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5
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3447739
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8 February 2020
Rosa Aligue
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6
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8 February 2020
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16 July 2012
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8 February 2020
published in
Molecular Cancer Research
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3447739
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8 February 2020
volume
10
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8 February 2020
issue
9
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PMC publication ID
3447739
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8 February 2020
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1189-1202
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3447739
reference URL
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8 February 2020
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ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance
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Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain
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The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells
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The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer
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Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes
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The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
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Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
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FoxM1 is required for execution of the mitotic programme and chromosome stability
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The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis
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Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
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1 October 2017
Chk2 activates E2F-1 in response to DNA damage
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1 October 2017
Cellular roles of dna topoisomerases: a molecular perspective
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1 October 2017
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1 October 2017
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
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1 October 2017
The winged-helix transcription factor Trident is expressed in cycling cells
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1 October 2017
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1 October 2017
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447739
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1 October 2017
Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases
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29 June 2018
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447739
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22 September 2018
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447739
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22 September 2018
Fluorescence-based quantitative scratch wound healing assay demonstrating the role of MAPKAPK-2/3 in fibroblast migration
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447739
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21 October 2018
Drug Resistance
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22802261
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1541-7786.MCR-11-0559
1 reference
stated in
Europe PubMed Central
PMC publication ID
3447739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802261%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMC publication ID
3447739
1 reference
stated in
Europe PubMed Central
PMC publication ID
3447739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802261%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed publication ID
22802261
1 reference
stated in
Europe PubMed Central
PMC publication ID
3447739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802261%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
ResearchGate publication ID
229156509
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