(Q22121990)

Dimensions Publication ID

Dimensions

1016798649

Nature Reviews Molecular Cell Biology

6 February 2023

language of work or name

English

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publication date

June 2002

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published in

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volume

3

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page(s)

430-440

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issue

6

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Investigating the biological functions of DNA topoisomerases in eukaryotic cells

21 January 2018

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DNA topoisomerases: structure, function, and mechanism

21 January 2018

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Interaction between DNA and an Escherichia coli protein omega.

21 January 2018

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Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

21 January 2018

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Catenation and knotting of duplex DNA by type 1 topoisomerases: a mechanistic parallel with type 2 topoisomerases

21 January 2018

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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine.

21 January 2018

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An atypical topoisomerase II from Archaea with implications for meiotic recombination

21 January 2018

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Genomics and early cellular evolution. The origin of the DNA world.

21 January 2018

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Structure and mechanism of DNA topoisomerase II

21 January 2018

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Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11

21 January 2018

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A model for the mechanism of strand passage by DNA gyrase

21 January 2018

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The organization of replication and transcription

21 January 2018

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Topological challenges to DNA replication: conformations at the fork

21 January 2018

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RecQ helicase and topoisomerase III comprise a novel DNA strand passage function: a conserved mechanism for control of DNA recombination

21 January 2018

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Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae

21 January 2018

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Essential functions of DNA topoisomerase I in Drosophila melanogaster.

21 January 2018

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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

21 January 2018

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Nature and distribution of chromosomal intertwinings in Saccharomyces cerevisiae

21 January 2018

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E. coli minichromosome replication: regulation of initiation at oriC.

21 January 2018

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Supercoiling of the DNA template during transcription

21 January 2018

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Hypothesis: chromosome separation in Escherichia coli involves autocatalytic gene expression, transertion and membrane-domain formation

21 January 2018

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Formation of supercoiling domains in plasmid pBR322.

21 January 2018

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Dynamics of DNA supercoiling by transcription in Escherichia coli

21 January 2018

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Anchoring of DNA to the bacterial cytoplasmic membrane through cotranscriptional synthesis of polypeptides encoding membrane proteins or proteins for export: a mechanism of plasmid hypernegative supercoiling in mutants deficient in DNA topoisomerase

21 January 2018

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Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I

21 January 2018

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Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes.

21 January 2018

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Isolation and characterization of a topA mutant of Shigella flexneri.

21 January 2018

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New topoisomerase essential for chromosome segregation in E. coli.

21 January 2018

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Coupled transcription and translation within nuclei of mammalian cells.

21 January 2018

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Targeting to transcriptionally active loci by the hydrophilic N-terminal domain of Drosophila DNA topoisomerase I.

21 January 2018

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Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene

21 January 2018

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Force and velocity measured for single molecules of RNA polymerase.

21 January 2018

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Nuclear bodies: multifaceted subdomains of the interchromatin space.

21 January 2018

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Protein dynamics: implications for nuclear architecture and gene expression.

21 January 2018

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Transcription through nucleosomes

21 January 2018

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DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates

21 January 2018

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DNA topoisomerase I is involved in both repression and activation of transcription

21 January 2018

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Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

21 January 2018

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Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

21 January 2018

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The role of DNA topoisomerases in recombination and genome stability: a double-edged sword?

21 January 2018

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Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

21 January 2018

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The importance of repairing stalled replication forks

21 January 2018

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DNA replication meets genetic exchange: chromosomal damage and its repair by homologous recombination

21 January 2018

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Type I topoisomerase activity is required for proper chromosomal segregation in Escherichia coli

21 January 2018

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A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

21 January 2018

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The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity

21 January 2018

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Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe

21 January 2018

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The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

21 January 2018

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Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae.

21 January 2018

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DNA helicases, genomic instability, and human genetic disease

21 January 2018

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The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases

21 January 2018

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RecQ helicases and topoisomerases: components of a conserved complex for the regulation of genetic recombination

21 January 2018

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Rothmund-thomson syndrome responsible gene, RECQL4: genomic structure and products

21 January 2018

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Mapping the DNA topoisomerase III binding domain of the Sgs1 DNA helicase

21 January 2018

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Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta

21 January 2018

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The essential role of yeast topoisomerase III in meiosis depends on recombination

21 January 2018

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Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease

21 January 2018

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Mechanism and control of meiotic recombination initiation

21 January 2018

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Reconstitution of DNA topoisomerase VI of the thermophilic archaeon Sulfolobus shibatae from subunits separately overexpressed in Escherichia coli

21 January 2018

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Mitotic chromosome condensation.

21 January 2018

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DNA segregation in bacteria.

21 January 2018

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Partitioning of the Escherichia coli chromosome: superhelicity and condensation

21 January 2018

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Shaping the metaphase chromosome: coordination of cohesion and condensation

21 January 2018

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DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

21 January 2018

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A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation

21 January 2018

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Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae.

21 January 2018

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The role of topoisomerase II in meiotic chromosome condensation and segregation in Schizosaccharomyces pombe

21 January 2018

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Role of DNA superhelicity in partitioning of the pSC101 plasmid

21 January 2018

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Effects of the pSC101 partition (par) locus on in vivo DNA supercoiling near the plasmid replication origin

21 January 2018

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Random diffusion can account for topA-dependent suppression of partition defects in low-copy-number plasmids

21 January 2018

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Suppression of chromosome segregation defects of Escherichia coli muk mutants by mutations in topoisomerase I.

21 January 2018

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Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II.

21 January 2018

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Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function.

21 January 2018

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Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II.

21 January 2018

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Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells

21 January 2018

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Molecular mechanisms of drug inhibition of DNA gyrase

21 January 2018

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DNA gyrase as a drug target

21 January 2018

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Tumor cell death induced by topoisomerase-targeting drugs.

21 January 2018

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Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibition

21 January 2018

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Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes

21 January 2018

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Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation

21 January 2018

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DNA topoisomerase IIbeta and neural development

21 January 2018

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A poxvirus-like type IB topoisomerase family in bacteria

21 January 2018

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Human mitochondrial topoisomerase I

21 January 2018

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Targeted disruption of the mouse topoisomerase I gene by camptothecin selection

21 January 2018

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Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis

21 January 2018

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Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan

21 January 2018

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The double-strand-break repair model for recombination

21 January 2018

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Identification of double Holliday junctions as intermediates in meiotic recombination.

21 January 2018

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Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

21 January 2018

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Replication fork arrest and DNA recombination

21 January 2018

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Resolution of Holliday junctions by eukaryotic DNA topoisomerase I

21 January 2018

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Renaturation of complementary single-stranded DNA circles: complete rewinding facilitated by the DNA untwisting enzyme

21 January 2018

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Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae.

21 January 2018

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The Bloom's syndrome gene product promotes branch migration of holliday junctions

21 January 2018

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Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvase

21 January 2018

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Identification of active site residues in Escherichia coli DNA topoisomerase I.

21 January 2018

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Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions

21 January 2018

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Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

21 January 2018

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DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

21 January 2018

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Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop

21 January 2018

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E. coli and M. luteus DNA topoisomerase I can catalyze catenation or decatenation of double-stranded DNA rings

31 March 2020

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Arrest of segregation leads to accumulation of highly intertwined catenated dimers: Dissection of the final stages of SV40 DNA replication

31 March 2020

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Escherichia coli DNA topoisomerase I mutants: Increased supercoiling is corrected by mutations near gyrase genes

31 March 2020

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Purification and characterization of a human factor that assembles and remodels chromatin

31 March 2020

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Metaphase chromosome structure. Involvement of topoisomerase II

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM831

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

674446

1016798649

0 references

674446

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference