(Q36249891)

13 August 2017

1 reference

title

The therapeutic potential of NS3 protease inhibitors in HCV infection (English)

1 reference

13 August 2017

Nathalie Goudreau

1

1 reference

13 August 2017

Montse Llinàs-Brunet

series ordinal

2

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 September 2005

1 reference

Expert Opinion on Investigational Drugs

13 August 2017

published in

1 reference

13 August 2017

volume

14

1 reference

13 August 2017

issue

9

1 reference

13 August 2017

page(s)

1129-1144

1 reference

Hepatitis C virus infection

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Genetic diversity and evolution of hepatitis C virus--15 years on

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

A nucleotide binding motif in hepatitis C virus (HCV) NS4B mediates HCV RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Hepatitis C virus NS5A: tales of a promiscuous protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Recent developments in the discovery of hepatitis C virus serine protease inhibitors--towards a new class of antiviral agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Promising candidates for the treatment of chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Diagnosis, management, and treatment of hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Modelling how ribavirin improves interferon response rates in hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

A zinc binding site in viral serine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Peptide-based inhibitors of the hepatitis C virus serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Potent peptide inhibitors of human hepatitis C virus NS3 protease are obtained by optimizing the cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Interferon regulatory factors: the next generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Product inhibition of the hepatitis C virus NS3 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Peptide-based inhibitors of the hepatitis C virus NS3 protease: structure-activity relationship at the C-terminal position.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: discovery of potent and specific tripeptide inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Potent inhibitors of the hepatitis C virus NS3 protease: design and synthesis of macrocyclic substrate-based beta-strand mimics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Sensitivity of NS3 serine proteases from hepatitis C virus genotypes 2 and 3 to the inhibitor BILN 2061.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Acyl sulfonamides as potent protease inhibitors of the hepatitis C virus full-Length NS3 (protease-helicase/NTPase): a comparative study of different C-terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Structure-activity relationships for the selectivity of hepatitis C virus NS3 protease inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Novel azapeptide inhibitors of hepatitis C virus serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Hepatitis C virus protease inhibitors: current progress and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl alpha-ketoamide based HCV protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

The design of potent, non-peptidic inhibitors of hepatitis C protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Toward a surrogate model for hepatitis C virus: An infectious molecular clone of the GB virus-B hepatitis agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Development of a GB virus B marmoset model and its validation with a novel series of hepatitis C virus NS3 protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

"Strong reasons make strong actions"--The antiviral efficacy of NS3/4A protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

Hepatitis C in adults and adolescents with hemophilia: a randomized, controlled trial of interferon alfa-2b and ribavirin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.9.1129

10.1517/13543784.14.9.1129

21 January 2018

Identifiers

DOI

1 reference

release_34cdptmzivfynlhzuxwqc723uq

13 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/34cdptmzivfynlhzuxwqc723uq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference