(Q42982898)

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In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

scientific article published on 6 February 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 November 2017

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Hepatitis C virus

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Chao Lin

1

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Kai Lin

2

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Europe PubMed Central

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12 November 2017

Yu-Ping Luong

3

1 reference

Europe PubMed Central

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12 November 2017

B Govinda Rao

4

1 reference

Europe PubMed Central

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12 November 2017

Yun-Yi Wei

5

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Europe PubMed Central

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12 November 2017

Debra L Brennan

6

1 reference

Europe PubMed Central

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12 November 2017

John R Fulghum

7

1 reference

Europe PubMed Central

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12 November 2017

Hsun-Mei Hsiao

8

1 reference

Europe PubMed Central

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12 November 2017

Sue Ma

9

1 reference

Europe PubMed Central

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12 November 2017

John P Maxwell

10

1 reference

Europe PubMed Central

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12 November 2017

Kevin M Cottrell

11

1 reference

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12 November 2017

Robert B Perni

12

1 reference

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12 November 2017

Cynthia A Gates

13

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12 November 2017

Ann D Kwong

14

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12 November 2017

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publication date

6 February 2004

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Europe PubMed Central

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12 November 2017

Journal of Biological Chemistry

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12 November 2017

279

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12 November 2017

17

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12 November 2017

17508-17514

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Europe PubMed Central

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12 November 2017

Epidemiology of hepatitis C: geographic differences and temporal trends

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Efficient initiation of HCV RNA replication in cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Prevalence and clinical correlates of YMDD variants during lamivudine therapy for patients with chronic hepatitis B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313020200

21 January 2018

Identifiers

10.1074/JBC.M313020200

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

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