(Q36250421)

13 August 2017

A RaPID way to discover nonstandard macrocyclic peptide modulators of drug targets (English)

1 reference

13 August 2017

1

Toby Passioura

1 reference

13 August 2017

Hiroaki Suga

2

1 reference

PubMed ID

28091672

13 August 2017

language of work or name

English

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publication date

16 January 2017

1 reference

13 August 2017

Chemical Communications

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13 August 2017

53

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13 August 2017

12

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13 August 2017

1931-1940

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Development of novel ligands for peptide GPCRs.

13 August 2017

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

The Pharmacological Potential of Non-ribosomal Peptides from Marine Sponge and Tunicates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A structural model for multimodular NRPS assembly lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

The echinocandin antifungals: an overview of the pharmacology, spectrum and clinical efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

The pharmacokinetics and pharmacodynamics of vancomycin in clinical practice: evidence and uncertainties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Targeting protein-protein interfaces using macrocyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Discovery of macrocyclic peptides armed with a mechanism-based warhead: isoform-selective inhibition of human deacetylase SIRT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

The exploration of macrocycles for drug discovery--an underexploited structural class

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

The evolution of genome mining in microbes - a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Tumor-targeting peptides from combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Selection-based discovery of druglike macrocyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

RNA-peptide fusions for the in vitro selection of peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

In vitro virus: bonding of mRNA bearing puromycin at the 3'-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

An in vitro evolved precursor tRNA with aminoacylation activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A ribozyme exclusively aminoacylates the 3'-hydroxyl group of the tRNA terminal adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Outersphere and innersphere coordinated metal ions in an aminoacyl-tRNA synthetase ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A versatile tRNA aminoacylation catalyst based on RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A highly flexible tRNA acylation method for non-natural polypeptide synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Using a solid-phase ribozyme aminoacylation system to reprogram the genetic code

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of peptidase-resistant peptides closed by a nonreducible inter-side-chain bond

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of dehydrobutyrine- and methyllanthionine-containing peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Diverse backbone-cyclized peptides via codon reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Initiating translation with D-amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Reevaluation of the D-amino acid compatibility with the elongation event in translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Translation initiation by using various N-acylaminoacyl tRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Reprogramming the translation initiation for the synthesis of physiologically stable cyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of polypeptoids and peptoid-peptide hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Messenger RNA-programmed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of an amphotericin-B inspired macrocycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Ribosomal synthesis of backbone-macrocyclic peptides containing γ-amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Synthesis of polyester by means of genetic code reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Polymerization of alpha-hydroxy acids by ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Translation initiation with initiator tRNA charged with exotic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A general method for site-specific incorporation of unnatural amino acids into proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Enzymatic aminoacylation of tRNA with unnatural amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

An expanded eukaryotic genetic code

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Cell-free translation reconstituted with purified components

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Programming peptidomimetic syntheses by translating genetic codes designed de novo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

In vitro selection of anti-Akt2 thioether-macrocyclic peptides leading to isoform-selective inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Synthesis of fused tricyclic peptides using a reprogrammed translation system and chemical modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Artificial human Met agonists based on macrocycle scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

A Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Expanding the amino acid repertoire of ribosomal polypeptide synthesis via the artificial division of codon boxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6CC06951G

21 January 2018

Identifiers

DOI

10.1039/C6CC06951G

1 reference

13 August 2017

1 reference

PubMed ID

28091672