(Q36251303)

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Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

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13 August 2017

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach (English)

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13 August 2017

DNA methylation

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Brian Chen

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17 January 2017

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Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.

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Blood lipids influence DNA methylation in circulating cells

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Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

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Mendelian randomization: applications and limitations in epigenetic studies

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1 October 2017

Differential DNA Methylation in Relation to Age and Health Risks of Obesity

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Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease

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1 October 2017

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

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Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

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Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

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Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

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Integrative analysis of 111 reference human epigenomes

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Genetic studies of body mass index yield new insights for obesity biology

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DNA methylation of lipid-related genes affects blood lipid levels

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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

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Large-scale association analysis identifies new risk loci for coronary artery disease

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

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Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease.

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

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Individuality and epigenetics in obesity.

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Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

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1 October 2017

Mapping the genetic architecture of gene expression in human liver

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1 October 2017

The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond

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1 October 2017

A mouse model of conditional lipodystrophy

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Role of malonyl-CoA in heart disease and the hypothalamic control of obesity

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The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947.

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1 October 2017

Generation of viable cholesterol-free mice

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1 October 2017

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

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1 October 2017

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

1 October 2017

Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

29 June 2018

The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob-ob mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

29 June 2018

BLUEPRINT to decode the epigenetic signature written in blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

22 September 2018

High density DNA methylation array with single CpG site resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

22 September 2018

Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

22 September 2018

Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

22 September 2018

Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

22 September 2018

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5240936

5 December 2018

Epidemiological approaches to heart disease: the Framingham Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28095459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of obesity on US mortality levels: the importance of age and cohort factors in population estimates

1 reference

https://pubmed.ncbi.nlm.nih.gov/28095459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel noninvasive diagnostic method for nonalcoholic steatohepatitis using two glycobiomarkers

1 reference

https://pubmed.ncbi.nlm.nih.gov/28095459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigation of coronary heart disease in families. The Framingham offspring study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28095459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenalectomy reverses pre-existing obesity in adult genetically obese (ob/ob) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28095459

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PMED.1002215

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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