(Q36256794)

22 May 2018

title

Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases (English)

1 reference

22 May 2018

12

Benjamin F Cravatt

1 reference

22 May 2018

9

Stephen Nayfach

1 reference

22 May 2018

Katherine Pollard

10

Katherine S Pollard

1 reference

22 May 2018

Michael A. Fischbach

15

Michael A Fischbach

1 reference

22 May 2018

Mohamed S. Donia

8

Mohamed S Donia

1 reference

22 May 2018

Keriann M Backus

4

Keriann M Backus

1 reference

22 May 2018

author name string

Chun-Jun Guo

1

1 reference

22 May 2018

Fang-Yuan Chang

2

1 reference

22 May 2018

Thomas P Wyche

3

1 reference

22 May 2018

Timothy M Acker

5

1 reference

22 May 2018

Masanori Funabashi

6

1 reference

22 May 2018

Mao Taketani

7

1 reference

22 May 2018

Charles S Craik

11

1 reference

22 May 2018

Jon Clardy

13

1 reference

22 May 2018

Christopher A Voigt

14

1 reference

22 May 2018

language of work or name

English

0 references

publication date

19 January 2017

1 reference

22 May 2018

published in

Cell

1 reference

22 May 2018

volume

168

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22 May 2018

issue

3

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22 May 2018

page(s)

517-526.e18

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22 May 2018

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Proteome-wide covalent ligand discovery in native biological systems

29 June 2018

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Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors

29 June 2018

1 reference

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HUMAN MICROBIOTA. Small molecules from the human microbiota

29 June 2018

1 reference

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MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome.

29 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.

29 June 2018

1 reference

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Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

29 June 2018

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Anatomical localization of commensal bacteria in immune cell homeostasis and disease

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Relating the metatranscriptome and metagenome of the human gut.

29 June 2018

1 reference

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Gut microbiota-generated metabolites in animal health and disease

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Detecting sequence homology at the gene cluster level with MultiGeneBlast

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Heterologous expression and structural characterisation of a pyrazinone natural product assembly line

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Host-gut microbiota metabolic interactions

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Metatranscriptomic approach to analyze the functional human gut microbiota

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Structure-based development of specific inhibitors for individual cathepsins and their medical applications

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Quantitative reactivity profiling predicts functional cysteines in proteomes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Inhibitors of cathepsin C (dipeptidyl peptidase I).

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Circular polymerase extension cloning of complex gene libraries and pathways

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Cathepsins are required for Toll-like receptor 9 responses

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Proteasome inhibitors: valuable new tools for cell biologists

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Use of peptide aldehydes to generate transition-state analogs of elastase

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Aldehydes as Inhibitors of Papain

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5302092

Biological activities of leupeptins

22 September 2018

1 reference

12 December 2020

Leupeptins, new protease inhibitors from Actinomycetes

1 reference

12 December 2020

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

1 reference

12 December 2020

Cysteine Proteases and Their Inhibitors

1 reference

12 December 2020

10.1016/J.CELL.2016.12.021

Identifiers

DOI

1 reference

22 May 2018

PMC publication ID

5302092

1 reference

22 May 2018

PubMed publication ID

28111075

1 reference

22 May 2018