(Q36275422)

13 August 2017

Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice (English)

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13 August 2017

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9

Peter B Dervan

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13 August 2017

8

Nicholas G Nickols

1 reference

13 August 2017

Timothy W Synold

1

1 reference

13 August 2017

Bixin Xi

2

1 reference

13 August 2017

Jun Wu

3

1 reference

13 August 2017

Yun Yen

4

1 reference

13 August 2017

Benjamin C Li

5

1 reference

13 August 2017

Fei Yang

6

1 reference

13 August 2017

John W Phillips

7

1 reference

13 August 2017

21 August 2012

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Cancer Chemotherapy and Pharmacology

13 August 2017

1 reference

13 August 2017

70

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13 August 2017

4

1 reference

13 August 2017

617-625

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https://scigraph.springernature.com/pub.10.1007/s00280-012-1954-3

13 August 2017

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cites work

Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Synthesis and biological properties of highly sequence-specific-alkylating N-methylpyrrole-N-methylimidazole polyamide conjugates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Inhibition of MMP-9 transcription and suppression of tumor metastasis by pyrrole-imidazole polyamide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Pharmacokinetic modeling and prediction of plasma pyrrole-imidazole polyamide concentration in rats using simultaneous urinary and biliary excretion data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Cyclic pyrrole-imidazole polyamides targeted to the androgen response element

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Completion of a Programmable DNA-Binding Small Molecule Library

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Improved nuclear localization of DNA-binding polyamides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Arresting cancer proliferation by small-molecule gene regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Drug handling by the lungs.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Determination of pyrrole-imidazole polyamide in rat plasma by liquid chromatography-tandem mass spectrometry

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Pharmacokinetics of pyrrole-imidazole polyamides after intravenous administration in rat.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseases

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

Solid-phase synthesis of DNA binding polyamides on oxime resin

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456924

10.1007/S00280-012-1954-3

22 September 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22907527

1 reference