(Q36277356)

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Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism.

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7 January 2020

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Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism (English)

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7 January 2020

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7 January 2020

author name string

Bernhard Stengl

1

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7 January 2020

Gerhard Klebe

3

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publication date

1 November 2005

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7 January 2020

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7 January 2020

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7 January 2020

1926-1939

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7 January 2020

11

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7 January 2020

Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Crystal structure of archaeosine tRNA-guanine transglycosylase

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

SCOP database in 2004: refinements integrate structure and sequence family data

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Assigning genomic sequences to CATH

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

CATH--a hierarchic classification of protein domain structures

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

The RNA modification database--1998.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Summary: the modified nucleosides of RNA.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Transfer RNA modification: influence on translational frameshifting and metabolism

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Biosynthesis of the modified nucleoside Q in transfer RNA

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

tRNA modification by S-adenosylmethionine:tRNA ribosyltransferase-isomerase. Assay development and characterization of the recombinant enzyme

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Characterization of cDNA encoding the human tRNA-guanine transglycosylase (TGT) catalytic subunit

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Transfer ribonucleic acid guanine transglycosylase isolated from rat liver

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Queuosine modification of tRNA: a case for convergent evolution

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Compilation of tRNA sequences and sequences of tRNA genes

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

RNA-modifying enzymes

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

tRNA-guanine transglycosylase from E. coli: a ping-pong kinetic mechanism is consistent with nucleophilic catalysis

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

tRNA-guanine transglycosylase from Escherichia coli: molecular mechanism and role of aspartate 89.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Structural principles of alpha/beta barrel proteins: the packing of the interior of the sheet

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

The evolution of alpha/beta barrel enzymes

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Homology among (betaalpha)(8) barrels: implications for the evolution of metabolic pathways

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

TopDraw: a sketchpad for protein structure topology cartoons

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

T-Coffee: A novel method for fast and accurate multiple sequence alignment

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

New wine from old barrels

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500063

21 January 2018

Identifiers

10.1002/CBIC.200500063

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16206323%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16206323%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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