(Q36278007)

13 August 2017

1 reference

title

Pharmacogenetics of folate-related drug targets in cancer treatment (English)

1 reference

13 August 2017

Kim Robien

1

1 reference

13 August 2017

Alanna Boynton

series ordinal

2

1 reference

13 August 2017

Cornelia M Ulrich

series ordinal

3

1 reference

13 August 2017

1 October 2005

1 reference

13 August 2017

1 reference

13 August 2017

6

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13 August 2017

7

1 reference

13 August 2017

673-689

1 reference

Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

13 August 2017

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Substrate flux through methylenetetrahydrofolate dehydrogenase: predicted effects of the concentration of methylenetetrahydrofolate on its partitioning into pathways leading to nucleotide biosynthesis or methionine regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Biological and clinical implications of the MTHFR C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Uracil misincorporation in human DNA detected using single cell gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Micronuclei in lymphocytes and exfoliated buccal cells of postmenopausal women with dietary changes in folate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Mutations in dihydropteroate synthase gene of Pneumocystis carinii in HIV patients with Pneumocystis carinii pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Rapid detection of dihydropteroate polymorphism in AIDS-related Pneumocystis carinii pneumonia by restriction fragment length polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Update on antifolate drugs targets

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Genetic polymorphism (G80A) of reduced folate carrier gene in ethnic populations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Pharmacogenetics and folate metabolism -- a promising direction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A Polymorphism, R653Q, in the Trifunctional Enzyme Methylenetetrahydrofolate Dehydrogenase/Methenyltetrahydrofolate Cyclohydrolase/Formyltetrahydrofolate Synthetase Is a Maternal Genetic Risk Factor for Neural Tube Defects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Identification of single nucleotide polymorphisms in the human γ-glutamyl hydrolase gene and characterization of promoter polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Pharmacogenetics and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Methylenetetrahydrofolate reductase C677T polymorphism and toxicity in allogeneic hematopoietic cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Pharmacogenetics of outcome in children with acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

The role of folic acid and Vitamin B12 in genomic stability of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

Effect of methylenetetrahydrofolate reductase 677C-->T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.6.7.673

21 January 2018

Identifiers

DOI

10.2217/14622416.6.7.673

1 reference

release_pdnkkiwvmvfbrjnmuedmulyqve

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pdnkkiwvmvfbrjnmuedmulyqve

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference