(Q36282129)

13 August 2017

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title

Inhibitors of proprotein convertases (English)

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13 August 2017

Ajoy Basak

1

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13 August 2017

publication date

8 October 2005

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Journal of Molecular Medicine

13 August 2017

published in

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13 August 2017

volume

83

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13 August 2017

issue

11

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13 August 2017

page(s)

844-855

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https://scigraph.springernature.com/pub.10.1007/s00109-005-0710-0

13 August 2017

exact match

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cites work

Localization of endogenous furin in cultured cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Inhibitory Effect of the .ALPHA.1-Antitrypsin Pittsburgh Type-Mutant(.ALPHA.1-PIM/R) on Proinsulin Processing in the Regulated Secretory Pathway of the Pancreatic .BETA.-Cell Line MIN6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Effects of L- and D-REKR amino acid-containing peptides on HIV and SIV envelope glycoprotein precursor maturation and HIV and SIV replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0710-0

Inhibitors of the subtilase-like pro-protein convertases (SPCs).

21 January 2018

1 reference

12 December 2020

Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin.

1 reference

12 December 2020

Folding pathway mediated by an intramolecular chaperone. The inhibitory and chaperone functions of the subtilisin propeptide are not obligatorily linked

1 reference

12 December 2020

Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin

1 reference

12 December 2020

The association of cardiovascular disease risk factors with abdominal obesity in Canada. Canadian Heart Health Surveys Research Group.

1 reference

12 December 2020

The peptidase zymogen proregions: nature's way of preventing undesired activation and proteolysis

1 reference

12 December 2020

Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters

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12 December 2020

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12 December 2020

Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands

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12 December 2020

The proprotein convertases

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12 December 2020

The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM)

1 reference

12 December 2020

Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin

1 reference

12 December 2020

Furin inhibition by compounds of copper and zinc

1 reference

12 December 2020

Proprotein convertases and the pathophysiology of human diseases: prospective considerations

1 reference

12 December 2020

Active site binding loop stabilization in the subtilisin inhibitor eglin c: structural and functional studies on specifically designed mutants in complex with subtilisin and the uncomplexed inhibitor

1 reference

12 December 2020

Proprotein convertases are important mediators of the adipocyte differentiation of mouse 3T3-L1 cells.

1 reference

12 December 2020

Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes

1 reference

12 December 2020

Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin

1 reference

12 December 2020

Synthesis of tight binding inhibitors and their action on the proprotein-processing enzyme furin

1 reference

12 December 2020

Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing

1 reference

12 December 2020

Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

1 reference

12 December 2020

1 reference

12 December 2020

Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor

1 reference

12 December 2020

Toward an enzyme/prodrug strategy for cancer gene therapy: endogenous activation of carboxypeptidase A mutants by the PACE/Furin family of propeptidases

1 reference

12 December 2020

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

1 reference

12 December 2020

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

1 reference

12 December 2020

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates

1 reference

12 December 2020

Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides

1 reference

12 December 2020

The pathogenesis and management of painful diabetic neuropathy: a review

1 reference

12 December 2020

Insulin biosynthesis: evidence for a precursor

1 reference

12 December 2020

Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins

1 reference

12 December 2020

Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library

1 reference

12 December 2020

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

12 December 2020

Polyarginines are potent furin inhibitors

1 reference

12 December 2020

Peptidyl substrates containing unnatural amino acid at the P'1 position are potent inhibitors of prohormone convertases

1 reference

12 December 2020

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

12 December 2020

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

1 reference

12 December 2020

Inhibition of convertase-related processing of proendothelin-1

1 reference

12 December 2020

Role of pro-IGF-II processing by proprotein convertase 4 in human placental development

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

1 reference

12 December 2020

The posttranslational phase of gene expression: new possibilities in molecular diagnosis

1 reference

12 December 2020

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

1 reference

12 December 2020

Structure-function analysis of the 7B2 CT peptide

1 reference

12 December 2020

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

1 reference

12 December 2020

The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein

1 reference

12 December 2020

Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1.

1 reference

12 December 2020

Modulating furin activity with designed mini-PDX peptides: synthesis and in vitro kinetic evaluation

1 reference

12 December 2020

Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.

1 reference

12 December 2020

The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

1 reference

12 December 2020

Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation

1 reference

12 December 2020

MEROPS: the peptidase database

1 reference

12 December 2020

Neuroendocrine secretory protein 7B2: structure, expression and functions

1 reference

12 December 2020

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

1 reference

12 December 2020

Enzymic characterization in vitro of recombinant proprotein convertase PC4.

1 reference

12 December 2020

Design and synthesis of novel inhibitors of prohormone convertases

1 reference

12 December 2020

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

1 reference

12 December 2020

Protease inhibitors formed in situ from copper and tridentate chelates: a generalized approach towards metal-based pharmaceuticals

1 reference

12 December 2020

Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus

1 reference

12 December 2020

Histidine-rich human salivary peptides are inhibitors of proprotein convertases furin and PC7 but act as substrates for PC1

1 reference

12 December 2020

Inhibition of soluble recombinant furin by human proteinase inhibitor 8

1 reference

12 December 2020

Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS.

1 reference

12 December 2020

alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent

1 reference

12 December 2020

Functional characterization of Narc 1, a novel proteinase related to proteinase K

1 reference

12 December 2020

Structure-function analysis of the prosegment of the proprotein convertase PC5A.

1 reference

12 December 2020

Posttranslational modification of therapeutic proteins in plants

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12 December 2020

Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor

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12 December 2020

Post-translational protein modification as the substrate for long-lasting memory

1 reference

12 December 2020

10.1007/S00109-005-0710-0

Identifiers

DOI

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13 August 2017

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