(Q36285943)

13 August 2017

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title

Animal models of sepsis: setting the stage (English)

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13 August 2017

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Jon A Buras

1

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13 August 2017

Bernhard Holzmann

series ordinal

2

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13 August 2017

Michail Sitkovsky

series ordinal

3

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13 August 2017

publication date

1 October 2005

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Nature Reviews Drug Discovery

13 August 2017

published in

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13 August 2017

volume

4

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13 August 2017

issue

10

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13 August 2017

page(s)

854-865

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

13 August 2017

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Animal models of sepsis and shock: a review and lessons learned.

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Why do animal models (sometimes) fail to mimic human sepsis?

31 March 2020

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Role of apoptotic cell death in sepsis

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Cytokines and anticytokines in the pathogenesis of sepsis

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31 March 2020

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Polymicrobial Sepsis but Not Low-Dose Endotoxin Infusion Causes Decreased Splenocyte IL-2/IFN-γ Release While Increasing IL-4/IL-10 Production

31 March 2020

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Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin

31 March 2020

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Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture

31 March 2020

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31 March 2020

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Role of Interferon- in Experimental Gram-Negative Sepsis

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Divergent role of gamma interferon in a murine model of pulmonary versus systemic Klebsiella pneumoniae infection

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Experimental models of gram-negative sepsis

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Role of interleukin-6 in mortality from and physiologic response to sepsis

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Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated interleukin 6 levels

31 March 2020

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Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis

31 March 2020

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CC chemokine receptor 2 regulates leukocyte recruitment and IL-10 production during acute polymicrobial sepsis

31 March 2020

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Critical role of Kupffer cell-derived IL-10 for host defense in septic peritonitis

31 March 2020

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Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection

31 March 2020

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Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis

31 March 2020

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Impaired monocyte IL-12 production before surgery as a predictive factor for the lethal outcome of postoperative sepsis

31 March 2020

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Prognostic factors for mortality in left colonic peritonitis: a new scoring system11No competing interests declared

31 March 2020

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Critical protective role of mast cells in a model of acute septic peritonitis

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Shock and tissue injury induced by recombinant human cachectin

31 March 2020

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Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

31 March 2020

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Treatment with recombinant human tumor necrosis factor-alpha protects rats against the lethality, hypotension, and hypothermia of gram-negative sepsis

31 March 2020

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31 March 2020

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Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis

31 March 2020

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Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner

31 March 2020

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31 March 2020

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31 March 2020

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Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies

31 March 2020

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Prognostic value of protein C concentrations in neutropenic patients at high risk of severe septic complications

31 March 2020

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Activated protein C versus protein C in severe sepsis

31 March 2020

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Association between the severity of sepsis and the changes in hemostatic molecular markers and vascular endothelial damage markers

31 March 2020

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Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

31 March 2020

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Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice.

31 March 2020

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A protein C deficiency exacerbates inflammatory and hypotensive responses in mice during polymicrobial sepsis in a cecal ligation and puncture model

31 March 2020

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Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial

31 March 2020

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Anti-complement Strategies in Experimental Sepsis

31 March 2020

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Sequential cardiorespiratory patterns in septic shock.

31 March 2020

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7 January 2021

Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis.

1 reference

7 January 2021

Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis.

1 reference

7 January 2021

Acute inflammatory response to endotoxin in mice and humans

1 reference

7 January 2021

Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia

1 reference

7 January 2021

Impact of interleukin-12, oxidative burst, and iNOS on the survival of murine fecal peritonitis

1 reference

7 January 2021

Identifiers

DOI

10.1038/NRD1854

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13 August 2017

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