(Q36290338)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

1 reference

1

1 reference

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13 February 2020

Giulia Di Lullo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Masayuki Amagai

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Takashi Hashimoto

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

15

Federica Sallusto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

12

Bungo Ohyama

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

17

Antonio Lanzavecchia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

9

Michael Hertl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

6

Fabrizia Vanzetta

1 reference

13 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

Davide Corti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Valentina Calabresi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Anna Sinistro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Biagio Didona

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Giuseppe Cianchini

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Rudiger Eming

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jerry Sloostra

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Giovanna Zambruno

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

4 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

122

1 reference

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13 February 2020

issue

10

1 reference

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13 February 2020

page(s)

3781-3790

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Detecting selection in immunoglobulin sequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Homologous regions of autoantibody heavy chain complementarity-determining region 3 (H-CDR3) in patients with pemphigus cause pathogenicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pathogenic anti-desmoglein MAbs show variable ELISA activity because of preferential binding of mature versus proprotein isoforms of desmoglein 3.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

IMGT, the international ImMunoGeneTics information system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Autoreactivity in human IgG+ memory B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

The evolution of human anti-double-stranded DNA autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Activation of Virus-specific Memory B Cells in the Absence of T Cell Help

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

C-cadherin ectodomain structure and implications for cell adhesion mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Lateral dimerization is required for the homophilic binding activity of C-cadherin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Clonal selection and learning in the antibody system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pemphigus vulgaris and pregnancy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris: a model for autoimmunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pemphigus vulgaris and pemphigus foliaceus sera show an inversely graded binding pattern to extracellular regions of desmosomes in different layers of human epidermis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pemphigus vulgaris antigen (desmoglein 3) is localized in the lower epidermis, the site of blister formation in patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Genetic characterization of human Dsg3-specific B cells isolated by flow cytometry from the peripheral blood of patients with pemphigus vulgaris

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Maintenance of serological memory by polyclonal activation of human memory B cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Structural elements controlling anti-DNA antibody affinity and their relationship to anti-phosphorylcholine activity.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Pathogenic anti-desmoglein 3 mAbs cloned from a paraneoplastic pemphigus patient by phage display

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Improved methods for detecting selection by mutation analysis of Ig V region sequences

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461925

Mucosal and mucocutaneous (generalized) pemphigus vulgaris show distinct autoantibody profiles

5 December 2018

1 reference

12 December 2020

An electron microscopic study of acantholysis in pemphigus vulgaris

1 reference

12 December 2020

In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris

1 reference

12 December 2020

IgG against extracellular subdomains of desmoglein 3 relates to clinical phenotype of pemphigus vulgaris

1 reference

12 December 2020

Immune response towards the amino-terminus of desmoglein 1 prevails across different activity stages in nonendemic pemphigus foliaceus

1 reference

12 December 2020

Epitope spreading is rarely found in pemphigus vulgaris by large-scale longitudinal study using desmoglein 2-based swapped molecules

1 reference

12 December 2020

Use of domain-swapped molecules for conformational epitope mapping of desmoglein 3 in pemphigus vulgaris

1 reference

12 December 2020

Dominant autoimmune epitopes recognized by pemphigus antibodies map to the N-terminal adhesive region of desmogleins

1 reference

12 December 2020

Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3

1 reference

12 December 2020

The Intercellular Cement in Pemphigus Vulgaris, an Electron Microscopic Study

1 reference

12 December 2020

Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease

1 reference

12 December 2020

Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response

1 reference

12 December 2020

Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI64413

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22996451%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference