(Q36300617)

13 August 2017

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma (English)

1 reference

13 August 2017

0 references

Unnur Þorsteinsdóttir

36

Unnur Thorsteinsdottir

0 references

Aslaug Jonasdottir

13

Aslaug Jonasdottir

0 references

Ingileif Jonsdottir

39

Ingileif Jonsdottir

0 references

Adalbjorg Jonasdottir

12

Adalbjorg Jonasdottir

0 references

Klaus Bønnelykke

33

Klaus Bønnelykke

1 reference

13 August 2017

19

Olof Sigurdardottir

1 reference

13 August 2017

Randal R Ketchem

9

0 references

Haruki Hasegawa

Haruki Hasegawa

7

0 references

Celeste Porsbjerg

Celeste Porsbjerg

27

0 references

Hans Bisgaard

Hans Bisgaard

34

0 references

Vibeke Backer

30

Vibeke Backer

1 reference

13 August 2017

21

Thorarinn Gislason

1 reference

13 August 2017

Patrick Sulem

3

1 reference

13 August 2017

Daníel F. Guðbjartsson

37

Daniel F Gudbjartsson

1 reference

13 August 2017

40

Kari Stefansson

1 reference

13 August 2017

29

Johannes Waage

1 reference

13 August 2017

Dirk Smith

1

1 reference

13 August 2017

Hannes Helgason

2

1 reference

13 August 2017

Unnur Steina Bjornsdottir

4

1 reference

13 August 2017

Ai Ching Lim

5

1 reference

13 August 2017

Gardar Sveinbjornsson

6

1 reference

13 August 2017

Michael Brown

8

1 reference

13 August 2017

Monica Gavala

10

1 reference

13 August 2017

Logan Garrett

11

1 reference

13 August 2017

Asgeir Sigurdsson

14

1 reference

13 August 2017

Olafur T Magnusson

15

1 reference

13 August 2017

Gudmundur I Eyjolfsson

16

1 reference

13 August 2017

Isleifur Olafsson

17

1 reference

13 August 2017

Pall Torfi Onundarson

18

1 reference

13 August 2017

David Gislason

20

1 reference

13 August 2017

Bjorn Runar Ludviksson

22

1 reference

13 August 2017

Dora Ludviksdottir

23

1 reference

13 August 2017

H Marike Boezen

24

1 reference

13 August 2017

Andrea Heinzmann

25

1 reference

13 August 2017

Marcus Krueger

26

1 reference

13 August 2017

Tarunveer S Ahluwalia

28

1 reference

13 August 2017

Klaus A Deichmann

31

1 reference

13 August 2017

Gerard H Koppelman

32

1 reference

13 August 2017

Gisli Masson

35

1 reference

13 August 2017

James A Johnston

38

1 reference

13 August 2017

8 March 2017

1 reference

13 August 2017

1 reference

13 August 2017

13

1 reference

13 August 2017

3

1 reference

13 August 2017

e1006659

1 reference

Creative Commons Attribution 4.0 International

13 August 2017

start time

8 March 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Weighting sequence variants based on their annotation increases power of whole-genome association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

YKL-40 and genetic status of CHI3L1 in a large group of asthmatics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Genetic associations with viral respiratory illnesses and asthma control in children.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Large-scale whole-genome sequencing of the Icelandic population

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Identification of a large set of rare complete human knockouts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

IL-33 is required for disposal of unnecessary cells during ovarian atresia through regulation of autophagy and macrophage migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Nonsense-mediated decay in genetic disease: friend or foe?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Role of interleukin 33 in respiratory allergy and asthma.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Resequencing candidate genes implicates rare variants in asthma susceptibility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A large-scale, consortium-based genomewide association study of asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A sequence variant on 17q21 is associated with age at onset and severity of asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Parental origin of sequence variants associated with complex diseases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Genetics of gene expression and its effect on disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A novel endonuclease IV post-PCR genotyping system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Genomewide screen for pulmonary function in 200 families ascertained for asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

The Sequence Ontology: a tool for the unification of genome annotations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Russell body inducing threshold depends on the variable domain sequences of individual human IgG clones and the cellular protein homeostasis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Eosinophils in the spotlight: Eosinophilic airway inflammation in nonallergic asthma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

An interleukin-33 gene polymorphism is a modifier for eosinophilia in rats

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

The Danish National Patient Register.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Rhinitis: a complication to asthma.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Polymorphisms in SPINK5 are not associated with asthma in a Dutch population

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Association study of the IL13 variant Arg110Gln in atopic diseases and juvenile idiopathic arthritis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362243

Interleukin-1 receptor–like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1006659

Genome-wide search for atopy susceptibility genes in Dutch families with asthma

21 January 2018

1 reference

12 December 2020

Blockade of IL-33/ST2 ameliorates airway inflammation in a murine model of allergic asthma

1 reference

12 December 2020

ST2 requires Th2-, but not Th17-, type airway inflammation in epicutaneously antigen- sensitized mice

1 reference

12 December 2020

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

1 reference

12 December 2020

IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation

1 reference

12 December 2020

The interleukin-33 receptor ST2 is important for the development of peripheral airway hyperresponsiveness and inflammation in a house dust mite mouse model of asthma

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1006659

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

28273074

1 reference