(Q36300994)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain (English)

1 reference

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9 February 2020

1 reference

1

1 reference

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9 February 2020

author name string

Lakshmi Menon

2

1 reference

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9 February 2020

Nataliya S Myshakina

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jinwoo Ahn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Michael A Parniak

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Rieko Ishima

6

1 reference

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9 February 2020

publication date

31 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

Chemical Biology and Drug Design

9 February 2020

published in

1 reference

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9 February 2020

volume

80

1 reference

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9 February 2020

issue

5

1 reference

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9 February 2020

page(s)

706-716

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

Identification of alternative binding sites for inhibitors of HIV-1 ribonuclease H through comparative analysis of virtual enrichment studies

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Interaction of HIV-1 reverse transcriptase ribonuclease H with an acylhydrazone inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

A hinge region cis-proline in ribonuclease A acts as a conformational gatekeeper for C-terminal domain swapping

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Domain Metastability: A Molecular Basis for Immunoglobulin Deposition?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Structure of HIV-1 Reverse Transcriptase with the Inhibitor β-Thujaplicinol Bound at the RNase H Active Site

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Probabilistic interaction network of evidence algorithm and its application to complete labeling of peak lists from protein NMR spectroscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Protein acrobatics in pairs--dimerization via domain swapping

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Novel HIV-1 reverse transcriptase inhibitors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

RNase H activity: structure, specificity, and function in reverse transcription

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Reverse transcription of the HIV-1 pandemic

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Non-nucleoside reverse transcriptase inhibitors (NNRTIs): past, present, and future

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Crystal structure of the moloney murine leukemia virus RNase H domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

The CCPN data model for NMR spectroscopy: development of a software pipeline

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Using NMRView to visualize and analyze the NMR spectra of macromolecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Oligomerization of bovine ribonuclease A: structural and functional features of its multimers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Complexity and simplicity of ligand-macromolecule interactions: the energy landscape perspective

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Characterization of a folding intermediate from HIV-1 ribonuclease H

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Unraveling principles of lead discovery: from unfrustrated energy landscapes to novel molecular anchors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Substitution of a highly basic helix/loop sequence into the RNase H domain of human immunodeficiency virus reverse transcriptase restores its Mn(2+)-dependent RNase H activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Nevirapine alters the cleavage specificity of ribonuclease H of human immunodeficiency virus 1 reverse transcriptase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Construction of an enzymatically active ribonuclease H domain of human immunodeficiency virus type 1 reverse transcriptase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Solution structural dynamics of HIV-1 reverse transcriptase heterodimer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodeficiency and murine leukemia retroviruses

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Importance of the positive charge cluster in Escherichia coli ribonuclease HI for the effective binding of the substrate.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465473

Parameters that influence the binding of human immunodeficiency virus reverse transcriptase to nucleic acid structures

29 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Backbone dynamics of the RNase H domain of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Theory of biomolecular recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Inhibitor binding alters the directions of domain motions in HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

Probing the local conformational change of alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12010

On the molecular weight and subunit composition of calf thymus ribonuclease H1

21 January 2018

1 reference

12 December 2020

Mechanism of DNA Strand Transfer Reactions Catalyzed by HIV-1 Reverse Transcriptase

1 reference

12 December 2020

Mutating a conserved motif of the HIV-1 reverse transcriptase palm subdomain alters primer utilization

1 reference

12 December 2020

Solution structure and dynamics of a serpin reactive site loop using interleukin 1beta as a presentation scaffold

1 reference

12 December 2020

Inhibitors of HIV-1 reverse transcriptase

1 reference

12 December 2020

Identifiers

DOI

10.1111/CBDD.12010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

22846652

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846652%20AND%20SRC:MED&resulttype=core&format=json