(Q36303805)

13 August 2017

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title

Drug therapy for atrial fibrillation: where do we go from here? (English)

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13 August 2017

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2

Dan M Roden

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13 August 2017

Richard L Page

1

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13 August 2017

1 November 2005

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Nature Reviews Drug Discovery

13 August 2017

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13 August 2017

4

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13 August 2017

899-910

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13 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrd1876

13 August 2017

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cites work

Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study

1 reference

Impact of atrial fibrillation on the risk of death: the Framingham Heart Study

21 January 2018

1 reference

Cost of an emerging epidemic: an economic analysis of atrial fibrillation in the UK

21 January 2018

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Tachycardia-induced cardiomyopathy: a reversible form of left ventricular dysfunction

21 January 2018

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Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins

21 January 2018

1 reference

Identifying and understanding the role of pulmonary vein activity in atrial fibrillation

21 January 2018

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Left atrial diameter in nonvalvular atrial fibrillation: An echocardiographic study. Stroke Prevention in Atrial Fibrillation Investigators

21 January 2018

1 reference

Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation

21 January 2018

1 reference

Inflammation as a risk factor for atrial fibrillation

21 January 2018

1 reference

Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs.

21 January 2018

1 reference

Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1.

21 January 2018

1 reference

Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats

21 January 2018

1 reference

Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation.

21 January 2018

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Reverse structural and gap-junctional remodeling after prolonged atrial fibrillation in the goat.

21 January 2018

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Altered pattern of connexin40 distribution in persistent atrial fibrillation in the goat

21 January 2018

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Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs

21 January 2018

1 reference

Outpatient treatment of recent-onset atrial fibrillation with the "pill-in-the-pocket" approach

21 January 2018

1 reference

Drug-induced prolongation of the QT interval

21 January 2018

1 reference

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

1 reference

Use of metoprolol CR/XL to maintain sinus rhythm after conversion from persistent atrial fibrillation: a randomized, double-blind, placebo-controlled study.

21 January 2018

1 reference

Antiarrhythmic effect of carvedilol after acute myocardial infarction: results of the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN) trial

21 January 2018

1 reference

VERDICT: the Verapamil versus Digoxin Cardioversion Trial: A randomized study on the role of calcium lowering for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation

21 January 2018

1 reference

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

21 January 2018

1 reference

A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression

21 January 2018

1 reference

Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current.

21 January 2018

1 reference

Dose-response relations of azimilide in the management of symptomatic, recurrent, atrial fibrillation

21 January 2018

1 reference

Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification

21 January 2018

1 reference

Electrophysiological effects of dronedarone (SR33589), a noniodinated benzofuran derivative, in the rabbit heart : comparison with amiodarone

21 January 2018

1 reference

Dronedarone for prevention of atrial fibrillation: a dose-ranging study.

21 January 2018

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Dronedarone: an amiodarone analogue

21 January 2018

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Safety and efficacy of intravenously administered tedisamil for rapid conversion of recent-onset atrial fibrillation or atrial flutter

21 January 2018

1 reference

Effect of the antifibrillatory compound tedisamil (KC-8857) on transmembrane currents in mammalian ventricular myocytes

21 January 2018

1 reference

The mechanism of atrial antiarrhythmic action of RSD1235.

21 January 2018

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A randomized, controlled trial of RSD1235, a novel anti-arrhythmic agent, in the treatment of recent onset atrial fibrillation

21 January 2018

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"Early" class III drugs for the treatment of atrial fibrillation: efficacy and atrial selectivity of AVE0118 in remodeled atria of the goat

21 January 2018

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Atrial effects of the novel K(+)-channel-blocker AVE0118 in anesthetized pigs.

21 January 2018

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Do human atrial 5-HT4 receptors mediate arrhythmias?

21 January 2018

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Trials of new antiarrhythmic drugs for maintenance of sinus rhythm in patients with atrial fibrillation

21 January 2018

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Ionic remodeling in the heart: pathophysiological significance and new therapeutic opportunities for atrial fibrillation

21 January 2018

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Calcium oscillations increase the efficiency and specificity of gene expression

21 January 2018

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Up-regulation of inositol 1,4,5 trisphosphate receptor expression in atrial tissue in patients with chronic atrial fibrillation

21 January 2018

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Pacing-induced spontaneous activity in myocardial sleeves of pulmonary veins after treatment with ryanodine

21 January 2018

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Defective cardiac ryanodine receptor regulation during atrial fibrillation

21 January 2018

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Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

21 January 2018

1 reference

Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs.

21 January 2018

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Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone

21 January 2018

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Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs

21 January 2018

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Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies Of Left Ventricular Dysfunction (SOLVD) trials

21 January 2018

1 reference

Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: a prospective and randomized study.

21 January 2018

1 reference

Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure

21 January 2018

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Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation.

21 January 2018

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Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease.

21 January 2018

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The HMG-CoA reductase inhibitor atorvastatin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis model

21 January 2018

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Stroke with intermittent atrial fibrillation: incidence and predictors during aspirin therapy. Stroke Prevention in Atrial Fibrillation Investigators

21 January 2018

1 reference

Atrial fibrillation as an independent risk factor for stroke: the Framingham Study

21 January 2018

1 reference

Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

21 January 2018

1 reference

Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin

21 January 2018

1 reference

Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the international multi-center feasibility trials.

21 January 2018

1 reference

Assessment of atrioventricular junction ablation and DDDR mode-switching pacemaker versus pharmacological treatment in patients with severely symptomatic paroxysmal atrial fibrillation: a randomized controlled study.

21 January 2018

1 reference

Pulmonary vein isolation for paroxysmal and persistent atrial fibrillation

21 January 2018

1 reference

Mortality, morbidity, and quality of life after circumferential pulmonary vein ablation for atrial fibrillation: outcomes from a controlled nonrandomized long-term study

21 January 2018

1 reference

Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial.

21 January 2018

1 reference

Rhythm or rate control in atrial fibrillation--Pharmacological Intervention in Atrial Fibrillation (PIAF): a randomised trial

21 January 2018

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A comparison of rate control and rhythm control in patients with atrial fibrillation

21 January 2018

1 reference

Rate control vs rhythm control in patients with nonvalvular persistent atrial fibrillation: the results of the Polish How to Treat Chronic Atrial Fibrillation (HOT CAFE) Study

21 January 2018

1 reference

Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study

21 January 2018

1 reference

Effect of rate or rhythm control on quality of life in persistent atrial fibrillation. Results from the Rate Control Versus Electrical Cardioversion (RACE) Study.

21 January 2018

1 reference

Clinical practice. Newly diagnosed atrial fibrillation

21 January 2018

1 reference

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

21 January 2018

1 reference

Familial atrial fibrillation is a genetically heterogeneous disorder.

21 January 2018

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Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation

21 January 2018

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KCNQ1 gain-of-function mutation in familial atrial fibrillation

21 January 2018

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A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation

21 January 2018

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A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene

21 January 2018

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Sudden death associated with short-QT syndrome linked to mutations in HERG.

21 January 2018

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Mutation in the KCNQ1 gene leading to the short QT-interval syndrome.

21 January 2018

1 reference

Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

21 January 2018

1 reference

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

21 January 2018

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Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease

21 January 2018

1 reference

Identification of a genetic locus for familial atrial fibrillation

21 January 2018

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Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy

21 January 2018

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Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit

21 January 2018

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Atrial fibrillation in KCNE1-null mice

21 January 2018

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Renin-angiotensin system gene polymorphisms and atrial fibrillation

21 January 2018

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Association of the human minK gene 38G allele with atrial fibrillation: evidence of possible genetic control on the pathogenesis of atrial fibrillation

21 January 2018

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Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization.

21 January 2018

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Experimental studies on auricular flutter and auricular fibrillation

21 January 2018

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A focal source of atrial fibrillation treated by discrete radiofrequency ablation

31 March 2020

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C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation

31 March 2020

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Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation

31 March 2020

1 reference

Ionic determinants of atrial fibrillation and Ca2+ channel abnormalities : cause, consequence, or innocent bystander?

31 March 2020

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Analysis of altered gene expression during sustained atrial fibrillation in the goat

31 March 2020

1 reference

International workshop on antithrombotic therapy for acute coronary syndromes. May 9-10, 1996, Como, Italy

31 March 2020

1 reference

Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort

31 March 2020

1 reference

Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators

31 March 2020

1 reference

Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction

31 March 2020

1 reference

Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents

31 March 2020

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Adrenergic modulation of ultrarapid delayed rectifier K+ current in human atrial myocytes

31 March 2020

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Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response. Azimilide Supraventricular Arrhythmia Program 3 (SVA-3) Investigators

31 March 2020

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Hotline sessions of the 26th European Congress of Cardiology

31 March 2020

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Atrial-specific drugs: the way to treat atrial fibrillation?

31 March 2020

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Azd7009: a new antiarrhythmic drug with predominant effects on the atria effectively terminates and prevents reinduction of atrial fibrillation and flutter in the sterile pericarditis model

31 March 2020

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Gene expression of proteins influencing the calcium homeostasis in patients with persistent and paroxysmal atrial fibrillation

31 March 2020

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Effect of verapamil on long-term tachycardia-induced atrial electrical remodeling

31 March 2020

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The T-type Ca(2+) channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs

31 March 2020

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Trandolapril reduces the incidence of atrial fibrillation after acute myocardial infarction in patients with left ventricular dysfunction

31 March 2020

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Inhibition of angiotensin II signaling and recurrence of atrial fibrillation in AFFIRM

31 March 2020

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The antiarrhythmic peptide analog ZP123 prevents atrial conduction slowing during metabolic stress

31 March 2020

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Tarantula peptide inhibits atrial fibrillation

31 March 2020

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31 March 2020

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A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation

31 March 2020

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The genetics of atrial fibrillation

31 March 2020

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Locus for atrial fibrillation maps to chromosome 6q14-16

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD1876

1 reference

PubMed ID

16264433

Dimensions Publication ID

13 August 2017

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1 reference

PubMed ID

16264433