(Q36304167)

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Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth

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Europe PubMed Central

PMC publication ID

13 August 2017

Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Michael P. Lisanti

9

object named as

Michael P Lisanti

1 reference

Europe PubMed Central

13 August 2017

PMC publication ID

Federica Sotgia

10

object named as

Federica Sotgia

1 reference

Europe PubMed Central

13 August 2017

PMC publication ID

Diana Whitaker-Menezes

4

object named as

Diana Whitaker-Menezes

1 reference

Europe PubMed Central

13 August 2017

PMC publication ID

Richard Pestell

8

object named as

Richard G Pestell

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ubaldo E Martinez-Outschoorn

3

object named as

Ubaldo E Martinez-Outschoorn

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Gloria Bonuccelli

2

object named as

Gloria Bonuccelli

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

7

object named as

Anthony Howell

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Valentina Carito

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Maria Cristina Caroleo

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Erika Cione

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

1 reference

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inferred from title

publication date

23 August 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

number of pages

12

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inferred from page(s)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

3403-3414

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Oxidative stress promotes myofibroblast differentiation and tumour spreading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Mammalian Rho GTPases: new insights into their functions from in vivo studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

TGFbeta in Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

The expression of migration stimulating factor, a potent oncofetal cytokine, is uniquely controlled by 3'-untranslated region-dependent nuclear sequestration of its precursor messenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Phenotypic and genetic alterations in mammary stroma: implications for tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Antifibrotic action of Cu/Zn SOD is mediated by TGF-beta1 repression and phenotypic reversion of myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Fibroblast subpopulations as accelerators of tumor progression: the role of migration stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Migration stimulating factor (MSF): its structure, mode of action and possible function in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

The tumor-promoting effect of wounding: a possible role for TGF-beta-induced stromal alterations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Foetal-to-adult transitions in fibroblast phenotype: their possible relevance to the pathogenesis of cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Purification of the migration stimulating factor produced by fetal and breast cancer patient fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Characterization of migration-stimulating factor (MSF): evidence for its role in cancer pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Heterogeneity amongst fibroblasts in the production of migration stimulating factor (MSF): Implications for cancer pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Hypothesis: persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

30 September 2017

Mitochondrial biogenesis drives tumor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Foetal and cancer patient fibroblasts produce an autocrine migration-stimulating factor not made by normal adult cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Antagonistic effects of TGF-beta 1 and MSF on fibroblast migration and hyaluronic acid synthesis. Possible implications for dermal wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

29 June 2018

Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts.

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

TGF-β signaling in development and disease.

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Occurence of stromal myofibroblasts in the invasive ductal breast cancer tissue is an unfavourable prognostic factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

22 September 2018

Migration-stimulating factor: a genetically truncated onco-fetal fibronectin isoform expressed by carcinoma and tumor-associated stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3466551

22 September 2018

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Occurrence of a fetal fibroblast phenotype in familial breast cancer

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

FIBROBLASTS FROM RELATIVES OF PATIENTS WITH HEREDITARY BREAST CANCER SHOW FETAL-LIKE BEHAVIOUR IN VITRO

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Migration stimulating activity in serum of breast cancer patients

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Phenotypic heterogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma

1 reference

https://api.crossref.org/works/10.4161%2FCC.21701

21 January 2018

Cancer associated fibroblasts stimulated by transforming growth factor beta1 (TGF-beta 1) increase invasion rate of tumor cells: a population study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of the migration stimulating factor produced by fetal and cancer patient fibroblasts: effect on hyaluronic and synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine production and TGF-beta 1-mediated effects on metabolism and viability in renal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal myofibroblasts predict disease recurrence for colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal-like fibroblasts: their production of migration-stimulating factor and role in tumor progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblasts from cancer patients display a mixture of both foetal and adult-like phenotypic characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Power surge: supporting cells "fuel" cancer cell mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22918248

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CC.21701

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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