(Q36306388)

13 August 2017

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title

Perspective: chromosomal aneuploidy in leukemia--lessons from down syndrome (English)

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13 August 2017

Shai Izraeli

1

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13 August 2017

publication date

1 March 2006

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13 August 2017

published in

Hematological Oncology

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13 August 2017

volume

24

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13 August 2017

issue

1

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13 August 2017

page(s)

3-6

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13 August 2017

cites work

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Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?

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Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.

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Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

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Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome

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Leukaemia -- a developmental perspective

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

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RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

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Down syndrome and leukemia: new insights into the epidemiology, pathogenesis, and treatment

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Acute leukaemia in children with Down syndrome: a population-based Nordic study

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Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer.

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Aetiology of acute leukaemia

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Childhood acute lymphoblastic leukaemia--current status and future perspectives

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Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952

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Equal frequency of TEL/AML1+ acute lymphoblastic leukemia in children with and without Down syndrome.

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7 January 2021

Identifiers

DOI

10.1002/HON.758

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13 August 2017

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