(Q36308965)

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Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1) (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

3

object named as

Andras Fiser

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Rongbao Zhao

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Daniel Sanghoon Shin

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

I David Goldman

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

11 July 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

American Journal of Physiology - Cell Physiology

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

303

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

C673-81

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3468349/fullTextXML

based on heuristic

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A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding

1 reference

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Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter

1 reference

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Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporter

1 reference

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Random mutagenesis of the proton-coupled folate transporter (SLC46A1), clustering of mutations, and the bases for associated losses of function

1 reference

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Mechanisms of membrane transport of folates into cells and across epithelia

1 reference

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Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption

1 reference

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Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption

1 reference

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Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

1 reference

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Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method

1 reference

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The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.

1 reference

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Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line

1 reference

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Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1.

1 reference

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The functional roles of the His247 and His281 residues in folate and proton translocation mediated by the human proton-coupled folate transporter SLC46A1.

1 reference

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Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues

1 reference

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A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function

1 reference

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The proton-coupled folate transporter: impact on pemetrexed transport and on antifolates activities compared with the reduced folate carrier

1 reference

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N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT).

1 reference

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Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.

1 reference

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The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption

1 reference

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Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption

1 reference

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MMM: a sequence-to-structure alignment protocol.

1 reference

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Multiple mapping method: a novel approach to the sequence-to-structure alignment problem in comparative protein structure modeling.

1 reference

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Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter

1 reference

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Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier.

1 reference

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Protein homology detection by HMM-HMM comparison

1 reference

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Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs

1 reference

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A prominent low-pH methotrexate transport activity in human solid tumors: contribution to the preservation of methotrexate pharmacologic activity in HeLa cells lacking the reduced folate carrier

1 reference

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Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

1 reference

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The HMMTOP transmembrane topology prediction server

1 reference

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30 September 2017

The PSIPRED protein structure prediction server

1 reference

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Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome

1 reference

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The Protein Data Bank

1 reference

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1 reference

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1 reference

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1 reference

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Hereditary folate malabsorption: a positively charged amino acid at position 113 of the proton-coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding.

1 reference

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1 reference

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1 reference

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Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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A dimerization motif for transmembrane α–helices

1 reference

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21 January 2018

Identifiers

10.1152/AJPCELL.00123.2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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