(Q36309653)

13 August 2017

1 reference

title

Genetic variations of tubular sodium reabsorption leading to "primary" hypertension: from gene polymorphism to clinical symptoms (English)

1 reference

13 August 2017

arterial hypertension

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author name string

Giuseppe Bianchi

series ordinal

1

1 reference

13 August 2017

1 December 2005

1 reference

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

13 August 2017

1 reference

13 August 2017

289

1 reference

13 August 2017

6

1 reference

13 August 2017

R1536-49

1 reference

The MARCKS brothers: a family of protein kinase C substrates

13 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

The 460Trp polymorphism of the human alpha-adducin gene is not associated with isolated systolic hypertension in elderly Australian Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Salt consumption, reactive oxygen species and cardiovascular ageing: a hypothetical link

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

The dietary sodium-blood pressure plot "stiffens".

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Carotid and Femoral Artery Stiffness in Relation to Three Candidate Genes in a White Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Carotid and femoral intima–media thickness in relation to three candidate genes in a Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin polymorphism in hypertensives of South African ancestry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Synergistic effect of α-adducin and ACE genes causes blood pressure changes with body sodium and volume expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin Gly460Trp polymorphism and renal hemodynamics in essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Na+, kidney, hypertension and genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Two point mutations within the adducin genes are involved in blood pressure variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin polymorphism: detection and impact on hypertension and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Association and linkage analysis of the alpha-adducin gene and blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Linkage but lack of association for blood pressure and the α-adducin locus in normotensive twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin polymorphism, salt sensitivity, nitric oxide excretion, and cardiovascular risk factors in normotensive Hispanics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Comparative effects of chronic ACE inhibition and AT1 receptor blocked losartan on cardiac hypertrophy and renal function in hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Gene expression changes associated with fibronectin-induced cardiac myocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and Is responsible for the decreased activity in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Lack of association between Gly460Trp polymorphism of alpha-adducin gene and salt sensitivity of blood pressure in Polish hypertensives

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Problems of reporting genetic associations with complex outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Nonnutritive flow impairs uptake of fatty acid by white muscles of the perfused rat hindlimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Renal mechanisms of genetic hypertension: from the molecular level to the intact organism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Experimental strategies for the genetic dissection of complex traits in animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Corcoran Lecture. Cardiovascular genomics and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Hypertension-linked mutation in the adducin alpha-subunit leads to higher AP2-mu2 phosphorylation and impaired Na+,K+-ATPase trafficking in response to GPCR signals and intracellular sodium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Na+/K+/Cl(-)-cotransporter mediated Rb+ fluxes in membrane vesicles from kidneys of normotensive and hypertensive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Sodium transport kinetics in erythrocytes and inside-out vesicles from Milan rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Role of Na+/Ca2+ exchange in regulating cytosolic Ca2+ in cultured human pulmonary artery smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Low-renin hypertension, altered sodium homeostasis, and an alpha-adducin polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Presence of a potential-sensitive Na+ transport across renal brush-border membrane vesicles from rats of the Milan hypertensive strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

alpha-Adducin gene and essential hypertension in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin: a physical model with implications for function in assembly of spectrin-actin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genetic associations in large versus small studies: an empirical assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

No association between alpha-adducin 460 polymorphism and essential hypertension in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin gene polymorphism is associated with essential hypertension in Chinese: a case-control and family-based study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin: Ca++-dependent association with sites of cell-cell contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Human alpha-adducin gene, blood pressure, and sodium metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Role of the adducin family genes in human essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Lack of association of 3 functional gene variants with hypertension in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Cardiovascular risk in relation to alpha-adducin Gly460Trp polymorphism and systolic pressure: a prospective population study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Molecular mechanisms of human hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Present status of genetic mechanisms in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin polymorphism affects renal proximal tubule reabsorption in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Plasma ouabain-like factor during acute and chronic changes in sodium balance in essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Adducin: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Role of the Gly460Trp polymorphism of the alpha-adducin gene in primary hypertension in Scandinavians

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Na,K-ATPase activity in renal tubule cells from Milan hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Oxidative stress in Dahl salt-sensitive hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Influence of the alpha-adducin and ACE gene polymorphism on the progression of autosomal-dominant polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

From animal models to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Linkage analysis of candidate genes and gene-gene interactions in chinese hypertensive sib pairs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Mechanisms of ageing: public or private?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Association between the alpha-adducin gene and hypertension in the HyperGEN Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Erythrocyte adducin differential properties in the normotensive and hypertensive rats of the Milan strain. Characterization of spleen adducin m-RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Oxygen radicals in cardiovascular-renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Lack of association between a biallelic polymorphism in the adducin gene and blood pressure in whites and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Pharmacogenetics of antihypertensive drug responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

ACE and α-Adducin Polymorphism as Markers of Individual Response to Diuretic Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Monogenic traits are not simple: lessons from phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Association between hypertension and the alpha-adducin, beta1-adrenoreceptor, and G-protein beta3 subunit genes in the Japanese population; the Suita study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

A genomic-systems biology map for cardiovascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genomics, proteomics and integrative "omics" in hypertension research

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genetics, statistics and human disease: analytical retooling for complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Blood pressure phenotypes in relation to the ??-adducin C1797T polymorphism in the European Project on Genes in Hypertension(EPOGH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

beta-Adducin polymorphisms, blood pressure, and sodium excretion in three European populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Polymorphism of gamma-adducin gene in genetic hypertension and mapping of the gene to rat chromosome 1q55.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Blood pressure in relation to three candidate genes in a Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Association between hypertension and variation in the alpha- and beta-adducin genes in a white population

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Salt, endogenous ouabain and blood pressure interactions in the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Renal function in relation to three candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Genetic factors associated with volume-sensitive hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

The use of animal models in the study of complex disease: all else is never equal or why do so many human studies fail to replicate animal findings?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Alpha-adducin G460W polymorphism, urinary sodium excretion, and blood pressure in community-based samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Hypertension-linked decrease in the expression of brain gamma-adducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Decrease in hypothalamic gamma adducin in rat models of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

Coupling of the Na+/Ca2+exchanger, Na+/K+ pump and sarcoplasmic reticulum in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

ADD1 460W Allele Associated With Cardiovascular Disease in Hypertensive Individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00441.2005

10.1152/AJPREGU.00441.2005

21 January 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16278339