(Q36315622)

English

Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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lipopolysaccharide

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phosphorylation

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author name string

M J Robinson

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

S Beinke

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

A Kouroumalis

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

P N Tsichlis

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

S C Ley

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

20 August 2007

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Europe PubMed Central

PMC publication ID

13 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

13 August 2017

27

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

7355-7364

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses

1 reference

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30 September 2017

Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation

1 reference

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30 September 2017

MAP kinase kinase kinases and innate immunity

1 reference

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30 September 2017

Phosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.

1 reference

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30 September 2017

Regulation of protein kinases; controlling activity through activation segment conformation

1 reference

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30 September 2017

IkappaB kinase is an essential component of the Tpl2 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Plat-E: an efficient and stable system for transient packaging of retroviruses

1 reference

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30 September 2017

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

1 reference

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30 September 2017

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169048

30 September 2017

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

1 reference

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30 September 2017

Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

1 reference

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30 September 2017

Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis

1 reference

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30 September 2017

Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase

1 reference

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Expression cDNA cloning of a serine kinase transforming gene

1 reference

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The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation

1 reference

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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

1 reference

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30 September 2017

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

1 reference

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29 June 2018

Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.

1 reference

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22 September 2018

Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals

1 reference

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Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

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High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

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22 September 2018

Identifiers

10.1128/MCB.00301-07

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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