(Q40507825)

21 September 2017

title

Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity (English)

1 reference

21 September 2017

0 references

Brenda S Luciano

1

1 reference

21 September 2017

Sang Hsu

2

1 reference

21 September 2017

Padma L Channavajhala

3

1 reference

21 September 2017

Lih-Ling Lin

4

1 reference

21 September 2017

John W Cuozzo

5

1 reference

21 September 2017

language of work or name

English

0 references

publication date

4 October 2004

1 reference

Journal of Biological Chemistry

21 September 2017

published in

1 reference

21 September 2017

volume

279

1 reference

21 September 2017

issue

50

1 reference

21 September 2017

page(s)

52117-52123

1 reference

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Cot kinase activates tumor necrosis factor-alpha gene expression in a cyclosporin A-resistant manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Dimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

The role of cytokines in the psoriatic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Tumor necrosis factor in the serum of patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Inflammatory markers and risk of developing type 2 diabetes in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Tumor necrosis factor-alpha inhibits insulin's stimulating effect on glucose uptake and endothelium-dependent vasodilation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Regulation of novel protein kinase C epsilon by phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403716200

21 January 2018

Identifiers

DOI

10.1074/JBC.M403716200

1 reference

21 September 2017

1 reference