(Q36316485)

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Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Yun-Chen Tien

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ke Liu

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Chad Pope

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Pengcheng Wang

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Xiaochao Ma

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Xiao-bo Zhong

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

23 September 2015

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

43

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1938-1945

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Translating dosages from animal models to human clinical trials--revisiting body surface area scaling

1 reference

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Relating human genetic variation to variation in drug responses

1 reference

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30 September 2017

Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver

1 reference

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30 September 2017

RNA sequencing reveals dynamic changes of mRNA abundance of cytochromes P450 and their alternative transcripts during mouse liver development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

1 reference

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30 September 2017

Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Roles of FGF19 in liver metabolism.

1 reference

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30 September 2017

Correlation of mRNA and protein in complex biological samples.

1 reference

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30 September 2017

Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation

1 reference

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30 September 2017

Three patterns of cytochrome P450 gene expression during liver maturation in mice.

1 reference

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30 September 2017

Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoter

1 reference

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30 September 2017

Dose translation from animal to human studies revisited

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30 September 2017

Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide.

1 reference

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30 September 2017

P450 induction alters paclitaxel pharmacokinetics and tissue distribution with multiple dosing

1 reference

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30 September 2017

Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span

1 reference

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30 September 2017

Sex differences in pharmacokinetics and pharmacodynamics

1 reference

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30 September 2017

Induction of drug metabolism: the role of nuclear receptors.

1 reference

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30 September 2017

Cytokine regulation of liver development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Interindividual variability in inhibition and induction of cytochrome P450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Cytochrome P450 3A: ontogeny and drug disposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Gender-related differences in pharmacokinetics and their clinical significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

1 reference

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30 September 2017

Human CYP2B6: expression, inducibility and catalytic activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

30 September 2017

Phenobarbital induction of hepatic CYP2B1 and CYP2B2: pretranscriptional and post-transcriptional effects of gender, adult age, and phenobarbital dose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4658495

29 June 2018

Effects of cytochrome P450 (CYP)2C19 polymorphisms on pharmacokinetics of phenobarbital in neonates and infants with seizures.

1 reference

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22 September 2018

Expression and Functional Analysis of Hepatic Cytochromes P450, Nuclear Receptors, and Membrane Transporters in 10- and 25-Week-Olddb/dbMice

1 reference

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Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro

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Dexamethasone exposure of neonatal rats modulates biliary lipid secretion and hepatic expression of genes controlling bile acid metabolism in adulthood without interfering with primary bile acid kinetics.

1 reference

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Neonatal seizures: multicenter variability in current treatment practices

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22 September 2018

beta-Catenin is critical for early postnatal liver growth.

1 reference

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22 September 2018

The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A.

1 reference

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22 September 2018

Drug treatment of neonatal seizures by neonatologists and paediatric neurologists

1 reference

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22 September 2018

Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin

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22 September 2018

Developmental expression of human hepatic CYP2C9 and CYP2C19.

1 reference

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22 September 2018

Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

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The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

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Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor

1 reference

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Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s.

1 reference

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The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study.

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Induction of hepatic microsomal CYP4A activity and of peroxisomal beta-oxidation by two non-steroidal anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/26400395

12 December 2020

based on heuristic

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Neonatal phenobarbital-induced defects in age- and sex-specific growth hormone profiles regulating monooxygenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/26400395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A population-based study of neonatal seizures in Fayette County, Kentucky

1 reference

https://pubmed.ncbi.nlm.nih.gov/26400395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/26400395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of neonatal seizures

1 reference

https://pubmed.ncbi.nlm.nih.gov/26400395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.115.066316

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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