(Q44881276)

7 December 2017

title

Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin (English)

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7 December 2017

6

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7 December 2017

Hongbing Wang

1

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7 December 2017

Stephanie Faucette

2

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7 December 2017

Rick Moore

3

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7 December 2017

Tatsuya Sueyoshi

4

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7 December 2017

Masahiko Negishi

5

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7 December 2017

language of work or name

English

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publication date

28 April 2004

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Journal of Biological Chemistry

7 December 2017

published in

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7 December 2017

volume

279

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7 December 2017

issue

28

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7 December 2017

page(s)

29295-29301

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Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes

7 December 2017

cites work

1 reference

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Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

21 January 2018

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

21 January 2018

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A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression

21 January 2018

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The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

21 January 2018

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Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

21 January 2018

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Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

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Direct expression of fluorescent protein-tagged nuclear receptor CAR in mouse liver

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Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 Cells

21 January 2018

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The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

21 January 2018

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Phenobarbital-elicited activation of nuclear receptor CAR in induction of cytochrome P450 genes

21 January 2018

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Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

21 January 2018

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

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Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR.

21 January 2018

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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

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Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors

21 January 2018

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

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Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products

21 January 2018

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Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

21 January 2018

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Antiepileptic drug intoxication: factors and their significance

21 January 2018

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The importance of drug interactions in epilepsy therapy

21 January 2018

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Clinical importance of hepatic cytochrome P450 in drug metabolism

21 January 2018

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Interactions between antiepileptic and chemotherapeutic drugs

21 January 2018

1 reference

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The course of seizure disorders in patients with malignant gliomas.

21 January 2018

1 reference

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Enantioselective induction of cyclophosphamide metabolism by phenytoin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400580200

21 January 2018

Identifiers

DOI

10.1074/JBC.M400580200

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7 December 2017

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