(Q28213013)

1

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Derek J Parks

2

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Linda B Moore

3

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Jon L Collins

4

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Bryan Goodwin

5

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Catherine A Stoltz

7

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Steven A Kliewer

8

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Millard H Lambert

9

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Timothy M Willson

10

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John T Moore

Journal of Biological Chemistry

11

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language of work or name

English

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publication date

9 May 2003

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published in

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volume

278

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issue

19

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page(s)

17277-83

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cites work

Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Role reversal: new insights from new ligands for the xenobiotic receptor CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Use of the nuclear receptor PXR to predict drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Species-specific responses of constitutively active receptor (CAR)-CYP2B coupling: lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

cyclosporine and liver transplantation: Will the midazolam test make blood level monitoring obsolete?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

Molecular basis of ethnic differences in drug disposition and response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

A common genetic defect in nicotine metabolism decreases risk for dependence and lowers cigarette consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300138200

21 January 2018

Identifiers

DOI

10.1074/JBC.M300138200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12611900

1 reference

Consolidated OpenCitations Corpus – April 2017