(Q36318166)

13 August 2017

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title

Unshackling the links between reovirus oncolysis, Ras signaling, translational control and cancer (English)

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13 August 2017

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Maya Shmulevitz

1

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13 August 2017

Paola Marcato

series ordinal

2

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13 August 2017

Patrick W K Lee

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 November 2005

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13 August 2017

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13 August 2017

24

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13 August 2017

7720-7728

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13 August 2017

52

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209041

13 August 2017

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cites work

Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Replication-selective viruses for cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Oncogenic Ras and its role in tumor cell invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Identification of carbohydrate-binding domains in the attachment proteins of type 1 and type 3 reoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Translational control: the cancer connection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Signalling by receptor tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

PKR, apoptosis and cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

To cycle or not to cycle: a critical decision in cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

RAS oncogenes: the first 30 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Reovirus oncolysis of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Reovirus as a novel oncolytic agent

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Guanine nucleotide exchange factors: activators of Ras superfamily proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Phase I trial of intravenous administration of PV701, an oncolytic virus, in patients with advanced solid cancers

21 January 2018

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The implications of structured 5' untranslated regions on translation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

Newcastle disease virus (NDV): brief history of its oncolytic strains

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

21 January 2018

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Ras caught in another affair: the exchange factors for Ral.

21 January 2018

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Role of the host cell in persistent viral infection: Coevolution of L cells and reovirus during persistent infection

21 January 2018

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7 January 2021

High CD46 receptor density determines preferential killing of tumor cells by oncolytic measles virus

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7 January 2021

Studies on reovirus receptors of L cells: virus binding characteristics and comparison with reovirus receptors of erythrocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Defective translational control facilitates vesicular stomatitis virus oncolysis

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7 January 2021

Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.

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7 January 2021

Regulation of translational initiation during cellular responses to stress

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7 January 2021

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins

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7 January 2021

Increasing complexity of Ras signaling.

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7 January 2021

Targets and mechanisms for the regulation of translation in malignant transformation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Reovirus therapy of tumors with activated Ras pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

A sigma 1 region important for hemagglutination by serotype 3 reovirus strains

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Ral-GTPases: approaching their 15 minutes of fame

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Cell signaling: life or death decisions of ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

The preferential cytotoxicity of reovirus for certain transformed cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Selection of a mutant S1 gene during reovirus persistent infection of L cells: role in maintenance of the persistent state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

1 reference

7 January 2021

Conditionally replicating herpes vectors for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: poly(A) tail, poly(A)-binding protein, and eukaryotic translation initiation factor 4G

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Role of cytoplasmic mRNP proteins in translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Endogenous inhibitors of the dsRNA-dependent eIF-2 alpha protein kinase PKR in normal and ras-transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Interferon resistance promotes oncolysis by influenza virus NS1-deletion mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Transcriptional upregulation of interferon-induced protein kinase, PKR, in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Inhibition of reovirus type 3 binding to host cells by sialylated glycoproteins is mediated through the viral attachment protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Antiviral actions of interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Cellular receptors for viruses: links to tropism and pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

1 reference

7 January 2021

Structural organization of mRNA complexes with major core mRNP protein YB-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Storage of messenger RNA in eukaryotes: envelopment with protein, translational barrier at 5' side, or conformational masking by 3' side?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Evidence that the epidermal growth factor receptor on host cells confers reovirus infection efficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Switching signals on or off by receptor dimerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

eIF-2 kinases: regulators of general and gene-specific translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Multiple Ras functions can contribute to mammalian cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Translational control of growth factor and proto-oncogene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209041

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209041

1 reference

release_exugcfksqfegroyk2poe3mgiju

13 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/exugcfksqfegroyk2poe3mgiju

24 November 2022

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