(Q36318668)

13 August 2017

Variable region identical immunoglobulins differing in isotype express different paratopes (English)

1 reference

13 August 2017

Alena Janda

1

0 references

David Cowburn

object named as

David Cowburn

series ordinal

4

0 references

Arturo Casadevall

series ordinal

5

object named as

Arturo Casadevall

1 reference

13 August 2017

Ertan Eryilmaz

2

1 reference

PMCID

3471687

13 August 2017

Antonio Nakouzi

series ordinal

3

1 reference

PMCID

3471687

13 August 2017

language of work or name

English

0 references

publication date

28 August 2012

1 reference

Journal of Biological Chemistry

13 August 2017

1 reference

13 August 2017

287

1 reference

13 August 2017

42

1 reference

13 August 2017

35409-35417

1 reference

Immunoglobulin isotype influences affinity and specificity

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Isotype modulates epitope specificity, affinity, and antiviral activities of anti-HIV-1 human broadly neutralizing 2F5 antibody

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Leveraging SBDD in protein therapeutic development: antibody engineering.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Nuclear spin relaxation in isotropic and anisotropic media

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Hidden alternative structures of proline isomerase essential for catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

NMR spectroscopy brings invisible protein states into focus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Nature and functions of autoantibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Structure and Dynamics of the P7 Protein from the Bacteriophage ϕ12

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Free-energy landscape of enzyme catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

The immunoglobulin constant region contributes to affinity and specificity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Exchanging murine and human immunoglobulin constant chains affects the kinetics and thermodynamics of antigen binding and chimeric antibody autoreactivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Intrinsic motions along an enzymatic reaction trajectory

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Clustal W and Clustal X version 2.0

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Self-aggregation of Cryptococcus neoformans capsular glucuronoxylomannan is dependent on divalent cations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Protein free energy landscapes remodeled by ligand binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Comparison of multiple Amber force fields and development of improved protein backbone parameters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Using NMRView to visualize and analyze the NMR spectra of macromolecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

UCSF Chimera--a visualization system for exploratory research and analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Mechanisms of tryptophan fluorescence shifts in proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

The three-dimensional structures of a polysaccharide binding antibody to Cryptococcus neoformans and its complex with a peptide from a phage display library: implications for the identification of peptide mimotopes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

How protein chemists learned about the hydrophobic factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

NMR-derived model for a peptide-antibody complex.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Carbon-13 NMR study of switch variant anti-dansyl antibodies: antigen binding and domain-domain interactions

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Identification of rare immunoglobulin switch variants using the ELISA spot assay

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Conformation and dynamics of an Fab'-bound peptide by isotope-edited NMR spectroscopy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

Variable domain-identical antibodies exhibit IgG subclass-related differences in affinity and kinetic constants as determined by surface plasmon resonance.

29 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Isothermal titration calorimetry reveals differential binding thermodynamics of variable region-identical antibodies differing in constant region for a univalent ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Variable-region-identical antibodies differing in isotype demonstrate differences in fine specificity and idiotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

A syngeneic idiotype is immunogenic when borne by IgM but tolerogenic when joined to IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

NMR identification of epitopes of Lyme disease antigen OspA to monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Design of a serine protease-like catalytic triad on an antibody light chain displayed on the yeast cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Synthetic peptide vaccines: the quest to develop peptide vaccines for influenza, HIV and Alzheimer's disease.

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471687

22 September 2018

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

The Immunoglobulin Heavy Chain Constant Region Affects Kinetic and Thermodynamic Parameters of Antibody Variable Region Interactions with Antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

An idiotypic determinant formed by both immunoglobulin constant and variable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.404483

The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction

21 January 2018

1 reference

12 December 2020

Can isotype switch modulate antigen-binding affinity and influence clonal selection?

1 reference

12 December 2020

Isotype can affect the fine specificity of an antibody for a polysaccharide antigen

1 reference

12 December 2020

Do immunoglobulins have proteolytic activity?

1 reference

12 December 2020

Antibodies elicited by a Cryptococcus neoformans-tetanus toxoid conjugate vaccine have the same specificity as those elicited in infection

1 reference

12 December 2020

Role of heavy chain constant domains in antibody-antigen interaction. Apparent specificity differences among streptococcal IgG antibodies expressing identical variable domains

1 reference

12 December 2020

Correlation between immune maturation and idiotypic network recognition

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.404483

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

3471687