(Q36318813)

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Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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author name string

Jundong Zhou

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Shuyu Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jing Xue

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jori Avery

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Jinchang Wu

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Stuart E Lind

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Wei-Qun Ding

7

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Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

29 August 2012

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Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

13 August 2017

287

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Europe PubMed Central

PMC publication ID

13 August 2017

42

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

35161-35169

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes

1 reference

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MicroRNA-181b and microRNA-9 mediate arsenic-induced angiogenesis via NRP1.

1 reference

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Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo

1 reference

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Effect of nitroxoline on angiogenesis and growth of human bladder cancer

1 reference

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MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells

1 reference

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ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro

1 reference

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Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis

1 reference

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Targeting the hypoxia-inducible factor (HIF) pathway in cancer.

1 reference

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30 September 2017

Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling

1 reference

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30 September 2017

PPARalpha signaling mediates the synergistic cytotoxicity of clioquinol and docosahexaenoic acid in human cancer cells

1 reference

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Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.

1 reference

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30 September 2017

Activation of PPARalpha inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines.

1 reference

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

1 reference

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30 September 2017

The role of hypoxia-inducible factors in tumorigenesis.

1 reference

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30 September 2017

PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471732

30 September 2017

Peroxisome proliferator-activated receptor alpha and gamma ligands inhibit the growth of human ovarian cancer

1 reference

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30 September 2017

Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer

1 reference

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30 September 2017

Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors

1 reference

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The role of the hypoxia-inducible factor in tumor metabolism growth and invasion.

1 reference

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30 September 2017

Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells.

1 reference

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30 September 2017

Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

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30 September 2017

Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt.

1 reference

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30 September 2017

Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways

1 reference

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Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471732

30 September 2017

Anticancer activity of the antibiotic clioquinol

1 reference

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Exploiting tumour hypoxia in cancer treatment

1 reference

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Targeting HIF-1 for cancer therapy

1 reference

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Molecular responses to hypoxia in tumor cells

1 reference

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Hypoxia--a key regulatory factor in tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471732

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1 reference

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von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

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Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.

1 reference

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Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor alpha/retinoid X receptor

1 reference

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Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

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PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1-dependent DNA binding and transactivation

1 reference

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1 reference

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12 December 2020

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Identifiers

10.1074/JBC.M112.367367

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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