(Q36330548)

13 August 2017

Complement C3a regulates Muc5ac expression by airway Clara cells independently of Th2 responses (English)

1 reference

13 August 2017

Patricia Dillard

1

1 reference

13 August 2017

Rick A Wetsel

series ordinal

2

1 reference

13 August 2017

Scott M Drouin

series ordinal

3

1 reference

13 August 2017

language of work or name

English

0 references

publication date

30 March 2007

1 reference

American Journal of Respiratory and Critical Care Medicine

13 August 2017

1 reference

13 August 2017

175

1 reference

13 August 2017

12

1 reference

13 August 2017

1250-1258

1 reference

C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

A protective role for the fifth complement component (c5) in allergic airway disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Airway mucus: From production to secretion.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Distinct regulation of C3a-induced MCP-1/CCL2 and RANTES/CCL5 production in human mast cells by extracellular signal regulated kinase and PI3 kinase.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

C3a enhances nerve growth factor-induced NFAT activation and chemokine production in a human mast cell line, HMC-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

A clinical and pathological study of fatal cases of status asthmaticus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Remodeling of the airway epithelium in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Expression of the complement anaphylatoxin C3a and C5a receptors on bronchial epithelial and smooth muscle cells in models of sepsis and asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Cutting edge: guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Pulmonary injury induced by C3a and C5a anaphylatoxins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Anaphylatoxin C3a enhances mucous glycoprotein release from human airways in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

RAG-1-deficient mice have no mature B and T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Epidermal growth factor receptor activation by epidermal growth factor mediates oxidant-induced goblet cell metaplasia in human airway epithelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Different mucins are produced by the surface epithelium and the submucosa in human trachea: identification of MUC5AC as a major mucin from the goblet cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Synergism between inflammatory mediators in vivo. Induction of airway hyperresponsiveness to C3a in the guinea pig.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Preservation of Tracheal Mucus by Nonaqueous Fixative

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Ultrastructure of lungs fixed in inflation using a new osmium-fluorocarbon technique

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression

29 June 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Complement factors C3a and C5a are increased in bronchoalveolar lavage fluid after segmental allergen provocation in subjects with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Two different transduction pathways are activated by C3a and C5a anaphylatoxins on astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Cholinergic agonists transactivate EGFR and stimulate MAPK to induce goblet cell secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176092

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

22 September 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200701-049OC

Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways

21 January 2018

1 reference

12 December 2020

Activation of human serum complement with allergens. I. Generation of C3a, C4a, and C5a and induction of human neutrophil aggregation

1 reference

12 December 2020

The structure of large and small airways in nonfatal and fatal asthma

1 reference

12 December 2020

Effect of house dust mite on serum complement activation and total haemolytic activity in vitro in normal subjects and in patients with bronchial asthma

1 reference

12 December 2020

Effect of exercise on complement activity

1 reference

12 December 2020

Identification of two glycoforms of the MUC5B mucin in human respiratory mucus. Evidence for a cysteine-rich sequence repeated within the molecule

1 reference

12 December 2020

Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy

1 reference

12 December 2020

In vitro complement activation by ragweed allergen extract in the sera of ragweed allergic and non-allergic persons

1 reference

12 December 2020

10.1164/RCCM.200701-049OC

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

17400733

1 reference